Regenerating Islet Derived Protein 4 (REG4)
GISP; REG-IV; RELP; Regenerating Gene Type IV; Gastrointestinal Secretory Protein; REG-like protein
The REG4 gene encodes a deduced 158-amino acid protein with an N-terminal signal peptide of 22 amino acids and a predicted molecular mass of 18.2 kD. REG4 maintains conservation of the 6 cysteine residues present in other known members of the REG family. By Northern blot analysis of intestinal mucosa from 12 individuals with inflammatory bowel disease, Hartupee et al. (2001) identified a 1.1-kb REG4 transcript in all samples. Control specimens had low but detectable expression of REG4. REG4 expression was significantly upregulated by inflammation and tissue injury associated with active Crohn disease and ulcerative colitis. RNA dot-blot analysis showed that most of the tissues expressing REG4 are in the gastrointestinal tract, i.e., colon, small intestine, stomach, and pancreas.
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant Regenerating Islet Derived Protein 4 (REG4) Recombinant Protein Customized Service Offer
- Monoclonal antibody MAB819Hu22 Monoclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) In Stock
- Polyclonal antibody PAB819Hu01 Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) In Stock
- Sandwich ELISA SEB819Hu ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPB819Mu01 Recombinant Regenerating Islet Derived Protein 4 (REG4) In Stock
- Recombinant protein RPB819Mu02 Recombinant Regenerating Islet Derived Protein 4 (REG4) In Stock
- Polyclonal antibody PAB819Mu01 Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) In Stock
- Polyclonal antibody PAB819Mu02 Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) In Stock
- Sandwich ELISA SEB819Mu ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPB819Ra01 Recombinant Regenerating Islet Derived Protein 4 (REG4) In Stock
- Polyclonal antibody PAB819Ra01 Polyclonal Antibody to Regenerating Islet Derived Protein 4 (REG4) In Stock
- Sandwich ELISA SEB819Ra ELISA Kit for Regenerating Islet Derived Protein 4 (REG4) In Stock