Seminal Vesicle Fibroblasts (SVF)

The seminal vesicles (SV) are a pair of glands that are positioned below the urinary bladder and lateral to the vas deferens. Each vesicle consists of a single tube folded and coiled on itself, with occasional diverticula in its wall. Seminal vesicles are located within the pelvis. The seminal vesicles secrete a significant proportion of the fluid that ultimately becomes semen.

 Fibroblasts are mesenchymal cells which perform many vital functions during development and in adulthood. They are responsible for much of the synthesis of extracellular matrix in connective tissue and play major roles in wound healing. Many diseases are associated with fibroblasts, either because fibroblasts are implicated in their etiology or because of the fibrosis that accompanies damage to other cell types. Fibroblasts are one of the most accessible mammalian cell types and one of the easiest types of cells to grow in culture. Seminal Vesicle Fibroblast Cells (SVF) is a model to study many features of the SV.