Solute Carrier Family 25, Member 46 (SLC25A46)

SLC25A46 belongs to the SLC25 family of mitochondrial carrier proteins.By searching databases for SLC25 family members, Haitina et al. (2006) identified SLC25A46. The deduced protein contains 347 amino acids. Quantitative real-time PCR detected variable expression in all rat tissues examined, with highest levels in hindbrain, spinal cord, and brain coronal sections containing corpus callosum, fornix, optic chiasm, thalamus, hypothalamus, midbrain, pons, and cerebellum.

Haitina et al. (2006) determined that the SLC25A46 gene contains 8 exons.By genomic sequence analysis, Haitina et al. (2006) mapped the SLC25A46 gene to chromosome 5. They mapped the mouse gene to chromosome 8.