T-47D Breast Ductal Carcinoma Cells (T-47D)

T-47D are epithelial cells isolated from a pleural effusion obtained from a 54-year-old female patient with an infiltrating ductal carcinoma of the breast. T-47D cell line is characterized by its estrogen receptor-positive (ER+) status, making it a valuable tool for studying hormone-responsive breast cancer. These cells exhibit high levels of both estrogen and progesterone receptors, allowing for the investigation of hormone-mediated signaling pathways and the effects of hormone therapies.

In addition to their hormone receptor status, T-47D cells have been found to exhibit characteristics of luminal subtype breast cancer, making them a relevant model for studying this particular subtype of the disease.

Overall, the T-47D cell line serves as a valuable tool for researchers looking to better understand the molecular mechanisms underlying breast cancer development and progression, as well as for testing potential therapeutic interventions.