T-Cell Interacting, Activating Receptor On Myeloid Cells Protein 1 (TARM1)

TARM1 Contains 2 Ig-like C2-type (immunoglobulin-like) domains.Immunoglobulin-like domains that are related in both sequence and structure can be found in several diverse protein families. Ig-like domains are involved in a variety of functions, including cell–cell recognition, cell-surface receptors, muscle structure and the immune system.The domains in Ig and Ig-like molecules are grouped into four types: V-set, C1-set , C2-set and I-set.

C2-set domains, which are Ig-like domains resembling the antibody constant domain. C2-set domains are found primarily in the mammalian T-cell surface antigens CD2 (Cluster of Differentiation 2), CD4 and CD80, as well as in vascular (VCAM) and intercellular (ICAM) cell adhesion molecules.