Tec Protein Tyrosine Kinase (TEC)

Tyrosine-protein kinase Tec is an enzyme belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain.

Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.