Tetrahydrofolic Acid (THFA)
H4FA; THF; Tetrahydrofolate
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Tetrahydrofolic acid is a folic acid derivative.It is a coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids. It acts as a donor of a group with one carbon atom. It gets this carbon atom by sequestering formaldehyde produced in other processes. A shortage in THF can cause megaloblastic anemia.
Tetrahydrofolic acid is reduced by the drug methotrexate, which is used to impair nucleotide synthesis. This drug is a potent chemotherapy and anti rheumatic.
Tetrahydrofolic acid is involved in the conversion of formiminoglutamic acid to glutamic acid; this may reduce the amount of histidine available for decarboxylation and protein synthesis, and hence the urinary histamine and formiminoglutamic acid may be decreased.
Organism species: Pan-species (General)
- Conjugated small molecules CPG411Ge11 BSA Conjugated Tetrahydrofolic Acid (THFA) In Stock
- Conjugated small molecules CPG411Ge21 OVA Conjugated Tetrahydrofolic Acid (THFA) In Stock
- Polyclonal antibody PAG411Ge01 Polyclonal Antibody to Tetrahydrofolic Acid (THFA) In Stock
- Competition ELISA CEG411Ge ELISA Kit for Tetrahydrofolic Acid (THFA) In Stock