Thyroxine (T4)
3,5,3',5'-Tetraiodothyronine; L-Thyroxine; Levothyroxine
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T4, the principal thyroid hormone largely bound to transport proteins, especially TBG. Given normal levels of thyroid hormone-binding proteins, hyperthyroidism is characterized by increased levels of circulating T4, hypothyroidism by decreased levels. Exceptions to this parallelism between thyroid status and total T4 concentration are found. Levels of TBG are known to be altered under various physiological, pharmacological and genetic conditions. Elevated T4 levels may be obtained when TBG levels are high, as in pregnancy, acute intermittent porphyria, hyperproteinemia, hereditary TBG elevation and in patients undergoing estrogen therapy or taking oral contraceptives. Total T4 levels may be depressed when TBG levels are low, as in nephrotic, hepatic, gastrointestinal and neoplastic disorders; in acromegaly, hypoproteinemia and hereditary TBG deficiency; and in patients undergoing androgen, testosterone or anabolic steroid therapy.
Organism species: Pan-species (General)
- Conjugated small molecules CPA452Ge11 BSA Conjugated Thyroxine (T4) In Stock
- Conjugated small molecules CPA452Ge21 OVA Conjugated Thyroxine (T4) In Stock
- Polyclonal antibody PAA452Ge01 Polyclonal Antibody to Thyroxine (T4) In Stock
- Labelled antibody LAA452Ge81 FITC-Linked Polyclonal Antibody to Thyroxine (T4) In Stock
- Monoclonal antibody MAA452Ge21 Monoclonal Antibody to Thyroxine (T4) In Stock
- Monoclonal antibody MAA452Ge22 Monoclonal Antibody to Thyroxine (T4) In Stock
- Monoclonal antibody MAA452Ge28 Monoclonal Antibody to Thyroxine (T4) In Stock
- Monoclonal antibody MAA452Ge25 Monoclonal Antibody to Thyroxine (T4) In Stock
- Monoclonal antibody MAA452Ge23 Monoclonal Antibody to Thyroxine (T4) In Stock
- Competition ELISA CEA452Ge ELISA Kit for Thyroxine (T4) In Stock
- Competition CLIA CCA452Ge CLIA Kit for Thyroxine (T4) In Stock
- Instant ELISA IEA452Ge Instant ELISA Kit for Thyroxine (T4) In Stock