Thyroxine Binding Globulin (TBG)
SERPINA7; Serpin Peptidase Inhibitor Clade A Member 7; T4-binding globulin
Thyroxine-binding globulin (TBG) binds Thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3’-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG is synthesized primarily in the liver as a 54 kDa protein. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins.
Organism species: Homo sapiens (Human)
- Recombinant protein RPA305Hu01 Recombinant Thyroxine Binding Globulin (TBG) In Stock
- Polyclonal antibody PAA305Hu01 Polyclonal Antibody to Thyroxine Binding Globulin (TBG) In Stock
- Monoclonal antibody MAA305Hu22 Monoclonal Antibody to Thyroxine Binding Globulin (TBG) In Stock
- Labelled antibody LAA305Hu81 FITC-Linked Polyclonal Antibody to Thyroxine Binding Globulin (TBG) In Stock
- Labelled antibody LAA305Hu71 Biotin-Linked Polyclonal Antibody to Thyroxine Binding Globulin (TBG) In Stock
- Sandwich ELISA SEA305Hu ELISA Kit for Thyroxine Binding Globulin (TBG) In Stock
- Sandwich CLIA SCA305Hu CLIA Kit for Thyroxine Binding Globulin (TBG) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPA305Mu01 Recombinant Thyroxine Binding Globulin (TBG) In Stock
- Recombinant protein RPA305Mu02 Recombinant Thyroxine Binding Globulin (TBG) In Stock
- Polyclonal antibody PAA305Mu01 Polyclonal Antibody to Thyroxine Binding Globulin (TBG) In Stock
- Polyclonal antibody PAA305Mu02 Polyclonal Antibody to Thyroxine Binding Globulin (TBG) In Stock
- Sandwich ELISA SEA305Mu ELISA Kit for Thyroxine Binding Globulin (TBG) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPA305Ra01 Recombinant Thyroxine Binding Globulin (TBG) In Stock
- Polyclonal antibody PAA305Ra01 Polyclonal Antibody to Thyroxine Binding Globulin (TBG) In Stock
- Sandwich ELISA SEA305Ra ELISA Kit for Thyroxine Binding Globulin (TBG) In Stock