Tyrosine Protein Kinase 7 (PTK7)
CCK4; Protein Tyrosine Kinase 7; Colon Carcinoma Kinase 4; Inactive tyrosine-protein kinase 7; Pseudo tyrosine kinase receptor 7
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Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene an intracellular domain with tyrosine kinase homology and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.
PTK7 serves as a context-dependent signalling switch for the Wnt pathways (particularly in planar cell polarity related functions such as convergent extension and neural crest cell migration) and appears to have similar functions for plexin and Flt-1 pathways.
Organism species: Homo sapiens (Human)
- Recombinant protein RPD247Hu01 Recombinant Tyrosine Protein Kinase 7 (PTK7) In Stock
- Recombinant protein RPD247Hu02 Recombinant Tyrosine Protein Kinase 7 (PTK7) In Stock
- Polyclonal antibody PAD247Hu01 Polyclonal Antibody to Tyrosine Protein Kinase 7 (PTK7) In Stock
- Labelled antibody LAD247Hu71 Biotin-Linked Polyclonal Antibody to Tyrosine Protein Kinase 7 (PTK7) In Stock
- Customized Service n/a CLIA Kit for Tyrosine Protein Kinase 7 (PTK7) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Tyrosine Protein Kinase 7 (PTK7) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Tyrosine Protein Kinase 7 (PTK7) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Tyrosine Protein Kinase 7 (PTK7) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Tyrosine Protein Kinase 7 (PTK7) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Tyrosine Protein Kinase 7 (PTK7) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Tyrosine Protein Kinase 7 (PTK7) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Tyrosine Protein Kinase 7 (PTK7) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Tyrosine Protein Kinase 7 (PTK7) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Tyrosine Protein Kinase 7 (PTK7) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Tyrosine Protein Kinase 7 (PTK7) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Tyrosine Protein Kinase 7 (PTK7) ELISA Kit Customized Service Offer