Zinc Finger Protein 100 (ZNF100)

Zinc Finger Protein 100 (ZNF100)
Zinc finger proteins (ZNFs), which bind nucleic acids, perform many key functions, the most important of which is regulating transcription. By PCR-based screening of a human genomic YAC library using degenerate oligonucleotides corresponding to a consensus sequence of the spacer region of ZNF91 family members, Bellefroid et al. (1993) identified 23 distinct ZNF91-related genes, including ZNF100. They demonstrated that members of the ZNF91 family are widely expressed in human tissues, with the highest expression in T-lymphoid cells.
Bellefroid et al. (1993) mapped YAC clones containing ZNF91-related genes by FISH and found that most of these genes, including ZNF100, are clustered in 19p13.1-p12.

Organism species: Homo sapiens (Human)