Zinc Finger Protein 99 (ZNF99)

C19orf9

Zinc Finger Protein 99 (ZNF99)
Zinc finger proteins (ZNFs), which bind nucleic acids, perform many key functions, the most important of which is regulating transcription. A zinc finger protein is a DNA-binding protein domain consisting of zinc fingers ranging from two in the Drosophila regulator ADR1, the more common three in mammalian Sp1 up to nine in TFIIIA.
Using probes derived from a ZNF91 cDNA to screen a pool of human chromosome 19-specific cosmids that had hybridized to a degenerate oligonucleotide corresponding to the H/C link region, Bellefroid et al. (1993) isolated the genes of several distinct ZNF91 subfamily members, including ZNF99. They found that ZNF91-related genes are widely expressed in human tissues, with the highest expression in T-lymphoid cells.

Organism species: Homo sapiens (Human)