Active Hedgehog Homolog, Indian (IHH) Homo sapiens (Human) Active protein

BDA1; HHG2

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Overview
Properties
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Pointn/a
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  • Active Hedgehog Homolog, Indian (IHH) Packages (Simulation)
  • Active Hedgehog Homolog, Indian (IHH) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Activity test

Usage

Reconstitute in 20mM Tris, 150mM NaCl (PH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Prostate cancer cells and bone stromal cells mutually interact with each other through bone morphogenetic protein-mediated signalsPubMed: 22532569
  • Defective CFTR promotes intestinal proliferation via inhibition of the hedgehog pathway during cystic fibrosisPubmed: 30639531
  • Eugenia Marbach-Breitrück, Madlen Matz-Soja, Ute Abraham, Wolfgang Schmidt-Heck, Susanne Sales, Christiane Rennert, Matthias Kern, Susanne Aleithe, Luise?…Pubmed: 30711403
  • Tick-Tock hedgehog–mutual crosstalk with liver circadian clock renders hepatic hedgehog signaling a risk factor of steatosis
  • MicroRNA-1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post-transcriptional suppression of Ihh expressionPubmed: 32705199

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