Active Interleukin 11 (IL11)

AGIF; Adipogenesis Inhibitory Factor; Oprelvekin

UOM
1. 10µg
2. 50µg
3. 200µg
4. 1mg
5. 5mg
FOB US$ 328.00 US$ 821.00 US$ 1,642.00 US$ 4,926.00 US$ 12,315.00
Quantity

Add to Cart Distributors

Overview

Properties

Product No.APA057Hu61
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
ApplicationsCell culture; Activity Assays.
Research use only
DownloadInstruction Manual
CategoryCytokine Infection immunity Rheumatology

Buffer FormulationPBS, pH7.4, containing 5% Trehalose.
Traits Freeze-dried powder, Purity > 95%
Isoelectric Point11.7

Share your citation Upload your experimental result Review Leave a message

Sign into your account

Email *

Password *

Verification code*

Create a new account

Share a new citation as an author

Title *

Journal

Link*

Upload your experimental result

Application*

Experimental result*

Review

Rating

Serial No* Please attach serial No. on instruction manual

Contact us
Please fill in the blank.

Name*

Organization

Address

E-mail address*

Telephone

Inquiry*

Verification code* CheckCode

Packages (Simulation)
Packages (Simulation)

Figure. SDS-PAGE
WB Image

ISO9001: 2008, ISO13485: 2003 Registered

Activity test

Interleukin 11 (IL-11) is a multifunctional cytokine. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses and participate in the regulation of bone cell proliferation and differentiation. Besides, IL-11 has been proved to promote cell proliferation of TF-1 cells. 2x104 TF-1 cells were seeded into a well of 96-well plates and allowed to attach, replaced with various concentrations of recombinant human TRAIL. After incubated for 72 hours, the 96-well plate was read at OD450 nm. The result was shown in Figure1. It was obvious that recombinant IL-11 protein significantly increased cell viability of TF-1 cells. Its EC50 is 0.5677μg/mL.

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.