Polyclonal Antibody to Complement 1q (C1q) Homo sapiens (Human) Polyclonal antibody

C1-q; Autoantigen Clq

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
  • TraitsLiquid, Concentration 0.5mg/mL
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  • Polyclonal Antibody to Complement 1q (C1q) Packages (Simulation)
  • Polyclonal Antibody to Complement 1q (C1q) Packages (Simulation)
  • Polyclonal Antibody to Complement 1q (C1q) Vector Red staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 20µg/ml Rabbit Anti-Human C1qA Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against C1q. It has been selected for its ability to recognize C1q in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease.PubMed: 22941511
  • Characterization of complement 1q binding protein of tiger shrimp, Penaeus monodon, and its C1q binding activityPubmed: 23085472
  • Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitisPubmed:27235358
  • The role of complement components C1q, MBL and C1 inhibitor in pathogenesis of endometriosisPubmed:29572748
  • Intrathecal complement activation by the classical pathway in tick-borne encephalitisPubmed: 30850976
  • Complement activation profile of patients with primary focal segmental glomerulosclerosisPubmed: 32569286
  • Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia33248023
  • Plasma and urine complement activation products in light chain and heavy chain deposition disease
  • Matrine treatment induced an A2 astrocyte phenotype and protected the blood-brain barrier in CNS autoimmunity34280490
  • Elevated Serum Complement C1q Levels After Traumatic Brain Injury and Its Association with Poor PrognosisPubmed:35035218

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