Polyclonal Antibody to Brain Natriuretic Peptide (BNP) Homo sapiens (Human) Polyclonal antibody

GC-B; B-Type Natriuretic Peptide; Ventricular Natriuretic Peptide; Gamma-brain natriuretic peptide; Brain natriuretic peptide 32

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Overview
Properties
  • SourcePolyclonal antibody preparation, Host Rabbit
  • Ig Type IgG, Potency n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen CPA541Hu21-OVA Conjugated Brain Natriuretic Peptide (BNP)
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 500µg/mL
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  • Polyclonal Antibody to Brain Natriuretic Peptide (BNP) Packages (Simulation)
  • Polyclonal Antibody to Brain Natriuretic Peptide (BNP) Packages (Simulation)
  • Polyclonal Antibody to Brain Natriuretic Peptide (BNP) Used in DAB staining on fromalin fixed paraffin- embedded liver tissue
  • PAA541Hu01.jpg WB Image
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a rabbit polyclonal antibody raised against BNP. It has been selected for its ability to recognize BNP in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Organism Species More: Mus musculus (Mouse), Rattus norvegicus (Rat)

Citations

  • B-type natriuretic peptide, vascular endothelial growth factor, endothelin-1, and nitric oxide synthase in chronic mountain sicknessAPS: source
  • Renalase deficiency in heart failure model of rats_a potential mechanism underlying circulating norepinephrine accumulation.PubMed: 21297953
  • Cardiac Troponin T and NT-proBNP as Biomarkers of Early Myocardial Damage in Amitriptyline-Induced Cardiovascular Toxicity in RatsPubmed: 24055824
  • ELEVATED ST2 SERUM LEVELS A BIOMARKER FOR CARDIOMYOPATHY IN DUCHENNE MUSCULAR DYSTROPHYOnlinejacc:Source
  • Why does Adenotonsillectomy Not Correct Enuresis in All Children with Sleep Disordered Breathing?Pubmed:24679871
  • Cardioprotective effects of baicalein on heart failure via modulation of Ca2PubMed: 26706290
  • Equine BNP measurement using a porcine BNP enzyme-linked immunoassay: a pilot studyPublication: 5950761
  • Renal Sympathetic Denervation Improves Cardiac DysfunctionPubMed: 25804096
  • Cardioprotective effects of baicalein on heart failure via modulation of Ca(2+) handling proteins in vivo and in vitroPubmed:26706290
  • Danhong injection attenuates isoproterenol-induced cardiac hypertrophy by reCavia (Guinea pig )lating p38 and NF-κb pathwayPubmed:26970569
  • Improvement in the prediction of exercise-induced elevation of left ventricular filling pressure in patients with normal left ventricular ejection fraction.pubmed:27779336
  • The effect of long-term amiodarone administration on myocardial fibrosis and evolution of left ventricular remodeling in a porcine model of ischemic …pubmed:27652141
  • Efficacy and Safety of Renal Sympathetic Denervation on Dogs with Pressure Overload-Induced Heart Failure.pubmed:27555054
  • Plasma concentration of fibronectin is decreased in patients with hypertrophic cardiomyopathypubmed:27693530
  • Paracrine cross-talk between skeletal muscle and macrophages in exercise by PGC-1α-controlled BNP.pubmed:28091624
  • Intermedin improves cardiac function and sympathetic neural remodeling in a rat model of post myocardial infarction heart failurepubmed:28627670
  • Enhanced heart failure, mortality and renin activation in female mice with experimental dilated cardiomyopathypubmed:29240788
  • Beneficial Effects of Renal Denervation on Cardiac Angiogenesis in Rats with Prolonged Pressure Overload pubmed:27575955
  • Metformin attenuated endotoxin-induced acute myocarditis via activating AMPKpubmed:28410530
  • Ginsenoside Rg3 micelles mitigate doxorubicin-induced cardiotoxicity and enhance its anticancer efficacy.pubmed:29063791
  • Co-exposure of silica nanoparticles and methylmercury induced cardiac toxicity andPubmed:29727991
  • An essential role for Wnt/β-catenin signaling in mediating hypertensive heart diseasePubmed:29895976
  • Cardioprotective effect of substance P in a porcine model of acute myocardial infarctionPubmed:29884290
  • High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failurePubmed:30072155
  • Acute Biochemical, Cardiovascular, and Autonomic Response to Hyperbaric (4 atm) Exposure in Healthy SubjectsPubmed:29977313
  • Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in ratsPubmed:29956781
  • Determinants of Increased Aortic Diameters in Young Normotensive Patients With Turner Syndrome Without Structural Heart DiseasePubmed:29392348
  • Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosisPubmed:29321061
  • 和肽素水平对大鼠心肾综合征的早期预测价值filename:ZBLS201802013
  • Signature-oriented investigation of the efficacy of multicomponent drugs against heart failurePubmed: 30230922
  • Long-term exposure to crotonaldehyde causes heart and kidney dysfunction through induction of inflammatory and oxidative damage in male Wistar ratsPubmed: 30426860
  • Van Veterinary Journal
  • Wnt/β-catenin signaling mediates both heart and kidney injury in type 2 cardiorenal syndromePubmed: 30770217
  • Inflammatory cytokines associated with cancer growth induce mitochondria and cytoskeleton alterations in cardiomyocytesPubmed: 30982981

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