Monoclonal Antibody to Vascular Endothelial Growth Factor 121 (VEGF121) Homo sapiens (Human) Monoclonal antibody

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG2b Kappa, Clone Number C5
  • PurificationProtein A + Protein G affinity chromatography
  • LabelNone
  • Immunogen RPB851Hu01-Recombinant Vascular Endothelial Growth Factor 121 (VEGF121)
  • Buffer Formulation0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/mL
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  • Monoclonal Antibody to Vascular Endothelial Growth Factor 121 (VEGF121) Packages (Simulation)
  • Monoclonal Antibody to Vascular Endothelial Growth Factor 121 (VEGF121) Packages (Simulation)
  • Monoclonal Antibody to Vascular Endothelial Growth Factor 121 (VEGF121) DAB staining on IHC-P; Sample: Human Lung cancer Tissue; Primary Ab: 30µg/ml Mouse Anti-Human VEGF121 Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • Monoclonal Antibody to Vascular Endothelial Growth Factor 121 (VEGF121) DAB staining on IHC-P;
    Sample: Human Liver Tissue;
    Primary Ab: 30µg/ml Mouse Anti-Human VEGF121 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Monoclonal Antibody to Vascular Endothelial Growth Factor 121 (VEGF121) DAB staining on IHC-P;
    Sample: Human Glioma Tissue;
    Primary Ab: 30µg/ml Mouse Anti-Human VEGF121 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Monoclonal Antibody to Vascular Endothelial Growth Factor 121 (VEGF121) DAB staining on IHC-P;
    Sample: Human Kidney Tissue;
    Primary Ab: 30µg/ml Mouse Anti-Human VEGF121 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Monoclonal Antibody to Vascular Endothelial Growth Factor 121 (VEGF121) DAB staining on IHC-P;
    Sample: Human Colorectal cancer Tissue;
    Primary Ab: 30µg/ml Mouse Anti-Human VEGF121 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against VEGF121. It has been selected for its ability to recognize VEGF121 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • Elevated PLGF contributes to small-cell lung cancer brain metastasisPubMed: 22797069
  • VEGF-121 plasma level as biomarker for response to anti-angiogenetic therapy in recurrent glioblastomaPubmed:29747600
  • A pediatric case of anaplastic astrocytoma with a gliomatosis cerebri; the growth pattern and changes in serum VEGF-121 levels after bevacizumab treatmentPubmed: 33222957
  • Associations between VEGF isoforms and impending retinopathy of prematurityPubmed: 32737903
  • Activin A triggers angiogenesis via regulation of VEGFA and its overexpression is associated with poor prognosis of oral squamous cell carcinomaPubmed: 32377747

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