A Disintegrin And Metalloprotease 17 (ADAM17)
CD156b; TACE; CSVP; Tumor Necrosis Factor,Alpha,Converting Enzyme; Disintegrin and metalloproteinase domain-containing protein 17; Snake venom-like protease
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ADAM17 is a 70-kDa enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases. ADAM17 is understood to be involved in the processing of tumor necrosis factor alpha (TNF-alpha;) at the surface of the cell, and from within the intracellular membranes of the trans-Golgi network. This process, which is also known as 'shedding', involves the cleavage and release of a soluble ectodomain from membrane-bound pro-proteins (such as pro-TNF-alpha;), and is of known physiological importance.
ADAM17 was the first 'sheddase' to be identified, and is also understood to play a role in the release of a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands, and enzymes.
Organism species: Homo sapiens (Human)
- Recombinant protein RPB555Hu01 Recombinant A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Polyclonal antibody PAB555Hu01 Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Monoclonal antibody MAB555Hu22 Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Labelled antibody LAB555Hu71 Biotin-Linked Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Labelled antibody LAB555Hu81 FITC-Linked Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Monoclonal antibody MAB555Hu21 Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Monoclonal antibody MAB555Hu24 Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Monoclonal antibody MAB555Hu23 Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Monoclonal antibody MAB555Hu25 Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Sandwich ELISA SEB555Hu ELISA Kit for A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant A Disintegrin And Metalloprotease 17 (ADAM17) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) Polyclonal Antibody Customized Service Offer
- Sandwich ELISA SEB555Mu ELISA Kit for A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPB555Ra01 Recombinant A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Polyclonal antibody PAB555Ra01 Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Monoclonal antibody MAB555Ra21 Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) In Stock
- Sandwich ELISA SEB555Ra ELISA Kit for A Disintegrin And Metalloprotease 17 (ADAM17) In Stock