Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) Homo sapiens (Human) Monoclonal antibody

CD156b; TACE; CSVP; Tumor Necrosis Factor,Alpha,Converting Enzyme; Disintegrin and metalloproteinase domain-containing protein 17; Snake venom-like protease

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Overview
Properties
  • SourceMonoclonal antibody preparation, Host Mouse
  • Ig Isotype IgG, Clone Number n/a
  • PurificationAntigen-specific affinity chromatography followed by Protein A affinity chromatography
  • LabelNone
  • Immunogen n/a
  • Buffer FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
  • TraitsLiquid, Concentration 1mg/mL
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  • Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) Packages (Simulation)
  • Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) Packages (Simulation)
  • Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) Western Blot; Samples: Lane1: Jurkat cell lysate; Lane2: A549 cell lysate;
    Primary Ab: 0.2µg/ml Mouse Anti-Human ADAM17 Antibody
    Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Specifity

The antibody is a mouse monoclonal antibody raised against ADAM17. It has been selected for its ability to recognize ADAM17 in immunohistochemical staining and western blotting.

Usage

Western blotting: 0.1-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Storage

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Citations

  • From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases.Pubmed:26991748
  • From varices to venous ulceration: the story of chronic venous disease described by metalloproteinasespubmed:26991748
  • ADAM17 regulates TNF-α expression upon lipopolysaccharide stimulation in oral keratinocytes.pubmed:28637950
  • L‐Selectin Expression Is Influenced by Phosphatase Activity in Chronic Lymphocytic LeukemiaPubmed: 30729673
  • Adamalysines as Biomarkers and a Potential Target of Therapy in Colorectal Cancer Patients: Preliminary ResultsPubmed: 31565100
  • PEG-SOD attenuates the mitogenic ERK1/2 signaling cascade induced by cyclosporin A in the liver and kidney of albino micePubmed: 32866465
  • High Levels of TNF-¦Á and TIM-3 as a Biomarker of Immune Reconstitution Inflammatory Syndrome in People with HIV Infection

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