Cross Linked C-Telopeptide Of Type I Collagen (CTXI)
CTX-I; CTX1;
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The carboxyterminal telopeptide of type I collagen (ICTP) is an indicator of degradation of type I collagen. ICTP antigen consists of a trivalent collagen cross-link joining three polypeptide chains of which two are α1 chains of one collagen molecule while the third is derived from either an α1 or an α2 chain of the helical region of another molecule (Fig. 1) (Risteli et al. 1993). The major determinant for antigeneity must contain two phenylalanine-rich regions, which is only possible if the cross-link is trivalent in nature (Sassi et al. 2000). In osteoclasts, catepsin K cleaves the trivalently cross-linked ICTP structure at two sites between the phenylalanine-rich region and the cross-link, thereby destroying any reactivity with ICTP antibodies (Sassi et al. 2000). Therefore degradation of type I collagen in bone is not measurable by the present ICTP-test. ICTP is cleared from circulation by the kidneys and has a molecular mass of about 12 000–20 000 (Risteli et al. 1993).
Organism species: Homo sapiens (Human)
- Synthetic polypeptide SPA665Hu01 Synthetic Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Conjugated small molecules CPA665Hu21 OVA Conjugated Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Conjugated small molecules CPA665Hu11 BSA Conjugated Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Conjugated small molecules CPA665Hu31 KLH Conjugated Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Polyclonal antibody PAA665Hu01 Polyclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Labelled antibody LAA665Hu71 Biotin-Linked Polyclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Labelled antibody LAA665Hu91 HRP-Linked Polyclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Hu21 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Labelled antibody LAA665Hu81 FITC-Linked Polyclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Labelled antibody LAA665Hu84 FITC-Linked Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Mi21 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Polyclonal antibody PAA665Hu02 Polyclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Mi22 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Mi23 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Mi24 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Mi25 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Mi26 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Mi27 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Competition ELISA CEA665Hu ELISA Kit for Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
Organism species: Mus musculus (Mouse)
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- Competition ELISA CEA665Mu ELISA Kit for Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
Organism species: Rattus norvegicus (Rat)
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- Monoclonal antibody MAA665Mi28 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Competition ELISA CEA665Ra ELISA Kit for Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
Organism species: Oryctolagus cuniculus (Rabbit)
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- Competition ELISA CEA665Rb ELISA Kit for Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
Organism species: Canis familiaris; Canine (Dog)
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- Monoclonal antibody MAA665Mi26 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Mi27 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
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Organism species: Bos taurus; Bovine (Cattle)
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- Monoclonal antibody MAA665Mi26 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Mi27 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
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Organism species: Ovis aries; Ovine (Sheep)
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- Competition ELISA CEA665Ov ELISA Kit for Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
Organism species: Chicken (Gallus)
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- Monoclonal antibody MAA665Mi26 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Mi27 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
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Organism species: Pan-species (General)
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- Polyclonal antibody PAA665Ge01 Polyclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
- Monoclonal antibody MAA665Ge21 Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI) In Stock
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