Chymase 1, Mast Cell (CMA1)
CYH; CYM; Alpha-chymase; Mast cell protease I
Chymase 1,Mast Cell(CMA1) is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides.
In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.
Organism species: Homo sapiens (Human)
- Recombinant protein RPG515Hu01 Recombinant Chymase 1, Mast Cell (CMA1) In Stock
- Polyclonal antibody PAG515Hu01 Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) In Stock
- Monoclonal antibody MAG515Hu21 Monoclonal Antibody to Chymase 1, Mast Cell (CMA1) In Stock
- Polyclonal antibody PAG515Hu02 Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) In Stock
- Sandwich ELISA SEG515Hu ELISA Kit for Chymase 1, Mast Cell (CMA1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPG515Mu01 Recombinant Chymase 1, Mast Cell (CMA1) In Stock
- Polyclonal antibody PAG515Mu01 Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) In Stock
- Labelled antibody LAG515Mu81 FITC-Linked Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) In Stock
- Labelled antibody LAG515Mu71 Biotin-Linked Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) In Stock
- Polyclonal antibody PAG515Mu02 Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) In Stock
- Sandwich ELISA SEG515Mu ELISA Kit for Chymase 1, Mast Cell (CMA1) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPG515Ra01 Recombinant Chymase 1, Mast Cell (CMA1) In Stock
- Polyclonal antibody PAG515Ra01 Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) In Stock
- Monoclonal antibody MAG515Ra21 Monoclonal Antibody to Chymase 1, Mast Cell (CMA1) In Stock
- Sandwich ELISA SEG515Ra ELISA Kit for Chymase 1, Mast Cell (CMA1) In Stock