Fascin (FSCN)
FSCN1; SNL; p55; Singed-like protein; 55 kDa actin-bundling protein; Fascin homolog 1, Actin-Bundling Protein(Strongylocentrotus Purpuratus); Singed,Drosophila,Homolog-Like
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FSCN is a 54-58 kilodalton monomeric actin filament bundling protein originally isolated from sea urchin egg but also found in Drosophila and vertebrates, including humans. Fascin (from the Latin for bundle) is spaced at 11 nanometre intervals along the filament. The bundles in cross section are seen to be hexagonally packed, and the longitudinal spacing is compatible with a model where fascin cross-links at alternating 4 and 5 actins.
It does seem likely that it may be most closely related to the fimbrin/plastin group since it is, like them, calcium insensitive, monomeric and close in apparent molecular mass.Fascin binds beta-catenin, and colocalizes with it at the leading edges and borders of epithelial and endothelial cells. Fascin is a protein encoded by the FSCN1 gene.
Organism species: Homo sapiens (Human)
- Recombinant protein RPB757Hu01 Recombinant Fascin (FSCN) In Stock
- Polyclonal antibody PAB757Hu01 Polyclonal Antibody to Fascin (FSCN) In Stock
- Monoclonal antibody MAB757Hu22 Monoclonal Antibody to Fascin (FSCN) In Stock
- Sandwich ELISA SEB757Hu ELISA Kit for Fascin (FSCN) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPB757Mu01 Recombinant Fascin (FSCN) In Stock
- Polyclonal antibody PAB757Mu01 Polyclonal Antibody to Fascin (FSCN) In Stock
- Labelled antibody LAB757Mu71 Biotin-Linked Polyclonal Antibody to Fascin (FSCN) In Stock
- Customized Service n/a CLIA Kit for Fascin (FSCN) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Fascin (FSCN) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPB757Ra01 Recombinant Fascin (FSCN) In Stock
- Polyclonal antibody PAB757Ra01 Polyclonal Antibody to Fascin (FSCN) In Stock
- Labelled antibody LAB757Ra71 Biotin-Linked Polyclonal Antibody to Fascin (FSCN) In Stock
- Customized Service n/a CLIA Kit for Fascin (FSCN) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Fascin (FSCN) ELISA Kit Customized Service Offer