Laminin Gamma 1 (LAMC1)
LAM-C1; LAMB2; S-laminin subunit gamma; Laminin B2 chain
LAMC1 is the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs seen on Northern analysis.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC082Hu01 Recombinant Laminin Gamma 1 (LAMC1) In Stock
- Polyclonal antibody PAC082Hu01 Polyclonal Antibody to Laminin Gamma 1 (LAMC1) In Stock
- Monoclonal antibody MAC082Hu22 Monoclonal Antibody to Laminin Gamma 1 (LAMC1) In Stock
- Labelled antibody LAC082Hu71 Biotin-Linked Polyclonal Antibody to Laminin Gamma 1 (LAMC1) In Stock
- Sandwich ELISA SEC082Hu ELISA Kit for Laminin Gamma 1 (LAMC1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPC082Mu01 Recombinant Laminin Gamma 1 (LAMC1) In Stock
- Polyclonal antibody PAC082Mu01 Polyclonal Antibody to Laminin Gamma 1 (LAMC1) In Stock
- Customized Service n/a CLIA Kit for Laminin Gamma 1 (LAMC1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Laminin Gamma 1 (LAMC1) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPC082Ra01 Recombinant Laminin Gamma 1 (LAMC1) In Stock
- Polyclonal antibody PAC082Ra01 Polyclonal Antibody to Laminin Gamma 1 (LAMC1) In Stock
- Customized Service n/a CLIA Kit for Laminin Gamma 1 (LAMC1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Laminin Gamma 1 (LAMC1) ELISA Kit Customized Service Offer