Leptin Receptor (LEPR)
CD295; LEPR; OBR; LR
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Leptin receptor functions as a receptor for the fat cell-specific hormone leptin. LEP-R has also been designated as CD295. After co-discovering the Leptin gene with Jeffrey Friedman et al. in 1994, which involved a reverse genetic/positional cloning strategy to clone ob and db, Rudolph Leibel, working with collaborators at Millennium Pharmaceuticals and colleague Streamson Chua, confirmed cloning of the leptin receptor by demonstrating that an apparent leptin receptor cloned from a choroid plexus library using leptin as ligand, mapped to a physical map that included db and fa. The leptin hormone regulates adipose-tissue mass through hypothalamus effects on fullness and energy use. It acts through the leptin receptor (LEP-R), a single-transmembrane-domain receptor of the cytokine receptor family.
Organism species: Homo sapiens (Human)
- Recombinant protein RPA083Hu01 Recombinant Leptin Receptor (LEPR) In Stock
- Active protein APA083Hu61 Active Leptin Receptor (LEPR) In Stock
- Eukaryotic protein EPA083Hu61 Eukaryotic Leptin Receptor (LEPR) In Stock
- Polyclonal antibody PAA083Hu01 Polyclonal Antibody to Leptin Receptor (LEPR) In Stock
- Monoclonal antibody MAA083Hu22 Monoclonal Antibody to Leptin Receptor (LEPR) In Stock
- Sandwich ELISA SEA083Hu ELISA Kit for Leptin Receptor (LEPR) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPA083Mu01 Recombinant Leptin Receptor (LEPR) In Stock
- Recombinant protein RPA083Mu02 Recombinant Leptin Receptor (LEPR) In Stock
- Polyclonal antibody PAA083Mu01 Polyclonal Antibody to Leptin Receptor (LEPR) In Stock
- Polyclonal antibody PAA083Mu02 Polyclonal Antibody to Leptin Receptor (LEPR) In Stock
- Labelled antibody LAA083Mu71 Biotin-Linked Polyclonal Antibody to Leptin Receptor (LEPR) In Stock
- Sandwich ELISA SEA083Mu ELISA Kit for Leptin Receptor (LEPR) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPA083Ra01 Recombinant Leptin Receptor (LEPR) In Stock
- Polyclonal antibody PAA083Ra01 Polyclonal Antibody to Leptin Receptor (LEPR) In Stock
- Monoclonal antibody MAA083Ra21 Monoclonal Antibody to Leptin Receptor (LEPR) In Stock
- Sandwich ELISA SEA083Ra ELISA Kit for Leptin Receptor (LEPR) In Stock
Organism species: Sus scrofa; Porcine (Pig)
- Recombinant protein RPA083Po01 Recombinant Leptin Receptor (LEPR) In Stock
- Polyclonal antibody PAA083Po01 Polyclonal Antibody to Leptin Receptor (LEPR) In Stock
- Customized Service n/a CLIA Kit for Leptin Receptor (LEPR) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Leptin Receptor (LEPR) ELISA Kit Customized Service Offer