Colitis

Colitis (pl. colitides) refers to an inflammation of the colon. Colitis may be acute and self-limited or chronic, i.e. persistent, and broadly fits into the category of digestive diseases.In a medical context, the label colitis (without qualification) is used if: The cause of the inflammation in the colon is undetermined; for example, colitis may be applied to Crohn's disease at a time when the diagnosis is unknown, or The context is clear; for example, an individual with ulcerative colitis is talking about their disease with a physician who knows the diagnosis. 

Models for Colitis are including models of ulcerative or chronic colitis induced by chemical drugs, such as acetic acid, dextran sulfate sodium(DSS), 2,4,6-trinitrobenzenesulfonic acid(TNBS) and 2,4-dinitrochlorobenzene etc.. A new ulcerative colitis model in rats by topical administration of sulfhydryl blockers. This model may be useful in studies on the pathogenesis of ulcerative colitis and the evaluation of drugs for therapy.