Substance P (SP)
In the field of neuroscience, substance P (SP) is a neuropeptide: an undecapeptide that functions as a neurotransmitter and as a neuromodulator. It belongs to the tachykinin neuropeptide family. Substance P and its closely related neuropeptide neurokinin A (NKA) are produced from a polyprotein precursor after differential splicing of the preprotachykinin A gene. The deduced amino acid sequence of substance P is as follows:Arg Pro Lys Pro Gln Gln Phe Phe Gly Leu Met
Substance P is released from the terminals of specific sensory nerves, it is found in the brain and spinal cord, and is associated with inflammatory processes and pain.Substance P was originally discovered in 1931 by Ulf von Euler and John H. Gaddum as a tissue extract that caused intestinal contraction in vitro. Its tissue distribution and biologic actions were further investigated over the following decades.
Organism species: Homo sapiens (Human)
- Synthetic polypeptide SPA393Hu01 Synthetic Substance P (SP) In Stock
- Conjugated small molecules CPA393Mi21 OVA Conjugated Substance P (SP) In Stock
- Polyclonal antibody PAA393Hu01 Polyclonal Antibody to Substance P (SP) In Stock
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Organism species: Mus musculus (Mouse)
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- Competition ELISA CEA393Mu ELISA Kit for Substance P (SP) In Stock
- Competition CLIA CCA393Mu CLIA Kit for Substance P (SP) In Stock
Organism species: Rattus norvegicus (Rat)
- Conjugated small molecules CPA393Mi21 OVA Conjugated Substance P (SP) In Stock
- Polyclonal antibody PAA393Ra01 Polyclonal Antibody to Substance P (SP) In Stock
- Competition ELISA CEA393Ra ELISA Kit for Substance P (SP) In Stock
- Competition CLIA CCA393Ra CLIA Kit for Substance P (SP) In Stock
Organism species: Cavia (Guinea pig )
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- Competition CLIA CCA393Gu CLIA Kit for Substance P (SP) In Stock
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Organism species: Canis familiaris; Canine (Dog)
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- Competition ELISA CEA393Ca ELISA Kit for Substance P (SP) In Stock
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Organism species: Bos taurus; Bovine (Cattle)
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- Competition CLIA CCA393Bo CLIA Kit for Substance P (SP) In Stock
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Organism species: Pan-species (General)
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- Competition ELISA CEA393Ge ELISA Kit for Substance P (SP) In Stock