Recombinant Alpha-2-Heremans Schmid Glycoprotein (AHSG) Bos taurus; Bovine (Cattle) Recombinant protein

aHSG; HSGa; A2HS; AHS; FETUA; HSG-A2; Fetuin-A; Alpha 2-HS Glycoprotein; Fetuin A; Alpha-2-Z-Globulin; Ba-alpha-2-Glycoprotein

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 40.1kDa, Accurate 48kDa(Analysis of differences refer to the manual)
  • Residues & TagsIle19~Ile359 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point4.9
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  • Recombinant Alpha-2-Heremans Schmid Glycoprotein (AHSG) Packages (Simulation)
  • Recombinant Alpha-2-Heremans Schmid Glycoprotein (AHSG) Packages (Simulation)
  • RPA178Bo01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Proteomic analysis reveals oxidative stress response as the main adaptative physiological mechanism in cows under different production systemsScienceDirect: S1874391912002084
  • Curcumin prevents liver fat accumulation and serum fetuin-A increase in rats fed a high-fat dietPubMed: 23430567
  • Serum Fetuin-A Levels Related with Microalbuminuria in Diet-Induced Obese RatsPubMed: PMC3591142
  • Estrogen increases the transcription of human α2-Heremans-Schmid-glycoprotein by an interplay of estrogen receptor α and activator protein-1.Pubmed: 24504099
  • A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefitsPubmed:25098735
  • Relationship Between Serum Fetuin-A Levels and Carotid Intima-media Thickness in Turkish Patients with Mild to Moderate Psoriasis. A Case-control StudyPubMed: 26476900
  • Fetuin A promotes lipotoxicity in β cells through the TLR4 signaling pathway and the role of pioglitazone in anti-lipotoxicity.PubMed: 25986658
  • Evaluation of Arterial Stiffness in Patients with BehPubMed: 26719639
  • Visceral and subcutaneous adipose tissue express and secrete functional alpha2hsglycoprotein (fetuin a) especially in obesitypubmed:27738888
  • Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humanspubmed:29212824
  • Acute Anti-Inflammatory Markers ITIH4 and AHSG in Mice Brain of a Novel Alzheimer's Disease ModelPubmed: 30958362
  • A New Serum Biomarker Set to Detect Mild Cognitive Impairment and Alzheimer's Disease by Peptidome TechnologyPubmed: 31771070
  • Ileal transposition helps to regulate plasma hepatokine levels in obese Zucker (Crl: ZUC (ORL)-Lepr fa) rats33833309
  • Predıctıve value of pregnancy of follıcular fluıd fetuın‐A and‐B levels ın infertıle women after intra‐cytoplasmic sperm injection34708901

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