Recombinant Amyloid Precursor Protein (APP)     
     
AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein
Overview
Properties
- Product No.RPB020Mu01
- Organism SpeciesMus musculus (Mouse) Same name, Different species.
- 
                                Applications
                                Positive Control; Immunogen; SDS-PAGE; WB.
 If bio-activity of the protein is needed, please check active protein.
 Research use only
- DownloadInstruction Manual
- CategoryNeuro science
- Source Prokaryotic expression, Host E.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationMembrane
- Molecular Mass 31.2kDa, Accurate 35kDa(Analysis of differences refer to the manual)
- Residues & TagsLeu18~Val286 with N-terminal His Tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- Traits Freeze-dried powder, Purity > 80%
- Isoelectric Point4.2
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            Sequence
 
                                        
                                    Usage
Reconstitute in ddH2O to a concentration of 0.1-0.2 mg/mL. Do not vortex.
Storage
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Increment services
- 
                 Endotoxin Removal Kit Endotoxin Removal Kit
- 
                 BCA Protein Quantification Kit BCA Protein Quantification Kit
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                 Protein Labeling Customized Service Protein Labeling Customized Service
- 
                 Molecular Mass Marker for Protein Molecular Mass Marker for Protein
- 
                 Recombinant Protein Customized Service Recombinant Protein Customized Service
- 
                 Monoclonal Antibody Customized Service Monoclonal Antibody Customized Service
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                 Polyclonal Antibody Customized Service Polyclonal Antibody Customized Service
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                 Protein Activity Test Experiment Service Protein Activity Test Experiment Service
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                 Immunoprecipitation (IP) Experiment Service Immunoprecipitation (IP) Experiment Service
- 
                 Buffer Buffer
- 
                 Endotoxin Removal Kit II Endotoxin Removal Kit II
- 
                 Real Time PCR Experimental Service Real Time PCR Experimental Service
- 
                 Spike RBD Protein (S-RBD) Spike RBD Protein (S-RBD)
- 
                 Protein G Protein G
- 
                 Protein A Protein A
Citations
- Bilobalide regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathwayScienceDirect: S0197018611001641
- Substitution of membrane cholesterol with β-sitosterol promotes nonamyloidogenic cleavage of endogenous amyloid precursor proteinPubmed: 23707801
- PROOF COVER SHEET
- (台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探
- Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in micePubmed: 32522471
- Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal …Pubmed:35312928
- The positive impact of 12 weeks of dance and balance training on the circulating amyloid precursor protein and serotonin concentration as well as physical and …Pubmed:35217193

 
         
    
     
                 
                 
                                 
                             
                