Recombinant Aromatase (ARO) Homo sapiens (Human) Recombinant protein

CYP19A1; CYPXIX; ARO; ARO1; CPV1; CYAR; CYP19; P450AROM; P450-AROM; Estrogen synthase; Cytochrome P450,Family 19,Subfamily A,Polypeptide 1

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Molecular Mass 22.0kDa, Accurate 24kDa(Analysis of differences refer to the manual)
  • Residues & TagsLeu196~Val373 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point5.4
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  • Recombinant Aromatase (ARO) Packages (Simulation)
  • Recombinant Aromatase (ARO) Packages (Simulation)
  • Recombinant Aromatase (ARO) Figure . Gene Sequencing (extract)
  • RPC319Hu01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Neonatal Testosterone Exposure Protects Adult Male Rats from StrokeKarger: 343804
  • Effects of Pomegranate Seed Oil and Tamoxifen on Mastectomy Breast Cancer WomenIosrphr: Source
  • Estrogen receptor 1 gene expression and its combination with estrogen receptor 2 or aromatase expression predicts survival in non-small cell lung cancer.Pubmed:25310221
  • Increased Expression of Pyloric ERβ Is Associated With Diabetic Gastroparesis in Streptozotocin-Induced Male Diabetic RatsGastrores:701
  • Modifications of Western-type diet regarding protein, fat and sucrose levels as modulators of steroid metabolism and activity in liverpubmed:27471150
  • 2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking studyPubmed: 32247112
  • Plasma Aromatase Activity Index, Gonadotropins and Estrone Are Associated with Frailty Syndrome in Post-Menopausal Women with Breast CancerPubmed:35323344

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