Recombinant Cathepsin K (CTSK) Homo sapiens (Human) Recombinant protein

CTS-K; CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD; Pycnodysostosis; Cathepsin O; Cathepsin X

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationLysosome
  • Molecular Mass 27.2kDa, Accurate 30kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla115~Met329 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point9.0
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  • Recombinant Cathepsin K (CTSK) Packages (Simulation)
  • Recombinant Cathepsin K (CTSK) Packages (Simulation)
  • Recombinant Cathepsin K (CTSK) Figure . Gene Sequencing (extract)
  • RPA267Hu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • MRMT-1 rat breast carcinoma cells and models of bone metastases: improvement of an in vitro system to mimic the in vivo condition.PubMed: S0065128112000773
  • Biochemical and clinical correlation of intraplaque neovascularization using contrast-enhanced ultrasound of the carotid arteryPubmed:24534452
  • Drynaria total flavonoids decrease cathepsin K expression in ovariectomized ratsPubmed:25036175
  • In vitro method for the screening and monitoring of estrogen-deficiency osteoporosis by targeting peripheral circulating monocytesPubMed: 26250906
  • Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary TuberculosisPubMed: 26416658
  • Effect of Vitamin D on Peripheral Blood Mononuclear Cells from Patients with Psoriasis Vulgaris and Psoriatic Arthritispmc:PMC4822855
  • TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42Pubmed:29358671
  • Comparative evaluation of cathepsin K levels in gingival crevicular fluid among smoking and nonsmoking patients with chronic periodontitisPubmed: 30409937
  • A bioactive exopolysaccharide from marine bacteria Alteromonas sp. PRIM-28 and its role in cell proliferation and wound healing in vitroPubmed: 30851325
  • Biomarkers of Compromised Implant Fixation
  • Compound K induces neurogenesis of neural stem cells in thrombin induced nerve injury through LXRα signaling in micePubmed: 32371156
  • Информационный алгоритм неинвазивной оценки остеорезорбтивного побочного действия глюкокортикостероидов у больных язвенным колитом
  • Особенности остеоиммунологических аспектов остеорезорбции при периимплантите, хроническом пародонтите и раке альвеолярного отростка и …

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