Recombinant Caveolin 1 (CAV1) Homo sapiens (Human) Recombinant protein

VIP21; Caveolae Protein 22kDa

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Molecular Mass 13.1kDa, Accurate 16kDa(Analysis of differences refer to the manual)
  • Residues & TagsSer2~Ser104 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Point5.7
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  • Recombinant Caveolin 1 (CAV1) Packages (Simulation)
  • Recombinant Caveolin 1 (CAV1) Packages (Simulation)
  • Recombinant Caveolin 1 (CAV1) Figure . Gene Sequencing (extract)
  • RPA214Hu01.png SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Novel prostate cancer tumour markers in a cell line modelMendelu: source
  • Caveolin-1 as a potential high-risk prostate cancer biomarkerPubMed: 22159333
  • Increased plasma caveolin-1 levels are associated with progression of prostate cancer among Japanese menPubmed: 23645736
  • Decrased sputum caveolin-1 is associated with systemic sclerosis related lung diseasePubmed:24751454
  • Significant Association of Caveolin-1 and Caveolin-2 with Prostate Cancer ProgressionPubMed: 26543085
  • Genomic variant in CAV1 increases susceptibility to coronary artery disease and myocardial infarctionPubmed:26775120
  • Increased caveolin-1 in intervertebral disc degeneration facilitates repairPubmed:26939667
  • Lower Serum Caveolin-1 Is Associated with Cerebral Microbleeds in Patients with Acute Ischemic StrokePubmed:27119011
  • Caveolin-1 Promotes the Imbalance of Th17/Treg in Patients with Chronic Obstructive PulmonaryDisease.pubmed:27613621
  • Swim Training Modulates Skeletal Muscle Energy Metabolism, Oxidative Stress, and Mitochondrial Cholesterol Content in Amyotrophic Lateral Sclerosis MicePubmed:29849903
  • Endothelium‐dependent hyperpolarization‐mediated vasodilatation compensates nitric oxide‐mediated endothelial dysfunction during ischemia in diabetes‐induced …Pubmed:29665152
  • The CAV1 Gene 3′ Untranslated Region Single Nucleotide Polymorphisms Are Associated with the Risk of Pulmonary Hypertension in Chinese Han Chronic …
  • SIRT6 transcriptionally regulates fatty acid transport by suppressing PPAR¦Ã34077730
  • Cav-1 Protein Levels in Serum and Infarcted Brain Correlate with Hemorrhagic Volume in a Mouse Model of Thromboembolic Stroke, Independently of Rt-PA?¡­
  • 5, 2′-Dibromo-2, 4′, 5′-trihydroxydiphenylmethanone Inhibits LPS-Induced Vascular Inflammation by Targeting the Cav1 ProteinPubmed:35566232

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