Recombinant Endothelial Cell Specific Molecule 1 (ESM1)
Endocan
Overview
Properties
- Product No.RPC463Hu01
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
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Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Research use only - DownloadInstruction Manual
- CategoryMetabolic pathwayTumor immunityInfection immunityCardiovascular biology
- Source Prokaryotic expression, Host E.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationSecreted
- Molecular Mass 19.6kDa, Accurate 19&44kDa(Analysis of differences refer to the manual)
- Residues & TagsTrp20~Arg184 with N-terminal His Tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- Traits Freeze-dried powder, Purity > 95%
- Isoelectric Point6.7
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Sequence

Usage
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Storage
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Increment services
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Endotoxin Removal Kit
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BCA Protein Quantification Kit
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Protein Labeling Customized Service
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Molecular Mass Marker for Protein
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Recombinant Protein Customized Service
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Monoclonal Antibody Customized Service
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Polyclonal Antibody Customized Service
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Protein Activity Test Experiment Service
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Immunoprecipitation (IP) Experiment Service
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Buffer
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Endotoxin Removal Kit II
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Real Time PCR Experimental Service
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Spike RBD Protein (S-RBD)
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Protein G
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Protein A
Citations
- Detection on dynamic changes of endothelial cell specific molecule-1 in acute rejection after renal transplantationPubMed: 22608803
- Endocan is useful biomarker of survival and severity in sepsis.Pubmed: 24769132
- Endocan, a putative endothelial cell marker, is elevated in preeclampsia, decreased in acute pyelonephritis, and unchanged in other obstetrical syndromesPubmed:25211383
- Endocan is useful biomarker of survival and severity in sepsisPubmed:24769132
- Endocan Levels and Subclinical Atherosclerosis in Patients With Systemic Lupus ErythematosusPubMed: 26614790
- Assessment of subclinical cardiac damage in chronic plaque psoriasis patients: a case control studyJournal:-102
- Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension.pubmed:27912147
- Diagnostic and prognostic values of endothelial-cell-specific molecule-1 with malignant pleural effusions in patients with non-small cell lung cancerpubmed:28514746
- Changes in Endocan Levels and Blood Coagulation in HIV InfectionDOI: 10.13005/bpj/1082
- A novel role of endocan in alleviating LPS-induced acute lung injuryPubmed:29627442
- Is the plasma endocan level a reliable predictor for the severity of erectile dysfunction?Pubmed:30054863
- Serum Level of Endothelial Cell-Specific Molecule-1 (ESM-1) as a New Potential Biomarker for Rheumatoid Arthritis Disease ActivityDoi: 10.2174/1874312901812010189
- Downregulation of ENDOCAN in myeloid leukemia cells inhibits proliferation and promotes apoptosis by suppressing nuclear factor‑κB activityPubmed: 30816462
- Endothelial biomarkers in the light of new sepsis definitionPubmed: 30920847
- Risk stratification and prognostic evaluation of endothelial cell‑specific molecule1, von Willebrand factor, and a disintegrin‑like and metalloprotease with …
- A novel marker relationship between carotid intima–media thickness and disease activity score-28 in patients with rheumatoid arthritis: human endothelial cell …Pubmed: 31655533
- Role of Ascitic Endocan Levels in the Diagnosis of Spontaneous Bacterial Peritonitis in Decompensated CirrhosisPubmed: 32364003
- Comparison of the maternal serum endocan levels in preterm premature rupture of membrane and normal pregnancy34109715
- The relationship between serum endocan levels with the presence of contrast-induced nephropathy in patients undergoing coronary angiography