Recombinant Endothelial Cell Specific Molecule 1 (ESM1) Homo sapiens (Human) Recombinant protein

Endocan

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 19.6kDa, Accurate 19&44kDa(Analysis of differences refer to the manual)
  • Residues & TagsTrp20~Arg184 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point6.7
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  • Recombinant Endothelial Cell Specific Molecule 1 (ESM1) Packages (Simulation)
  • Recombinant Endothelial Cell Specific Molecule 1 (ESM1) Packages (Simulation)
  • Recombinant Endothelial Cell Specific Molecule 1 (ESM1) Figure . Gene Sequencing (extract)
  • RPC463Hu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Detection on dynamic changes of endothelial cell specific molecule-1 in acute rejection after renal transplantationPubMed: 22608803
  • Endocan is useful biomarker of survival and severity in sepsis.Pubmed: 24769132
  • Endocan, a putative endothelial cell marker, is elevated in preeclampsia, decreased in acute pyelonephritis, and unchanged in other obstetrical syndromesPubmed:25211383
  • Endocan is useful biomarker of survival and severity in sepsisPubmed:24769132
  • Endocan Levels and Subclinical Atherosclerosis in Patients With Systemic Lupus ErythematosusPubMed: 26614790
  • Assessment of subclinical cardiac damage in chronic plaque psoriasis patients: a case control studyJournal:-102
  • Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension.pubmed:27912147
  • Diagnostic and prognostic values of endothelial-cell-specific molecule-1 with malignant pleural effusions in patients with non-small cell lung cancerpubmed:28514746
  • Changes in Endocan Levels and Blood Coagulation in HIV InfectionDOI: 10.13005/bpj/1082
  • A novel role of endocan in alleviating LPS-induced acute lung injuryPubmed:29627442
  • Is the plasma endocan level a reliable predictor for the severity of erectile dysfunction?Pubmed:30054863
  • Serum Level of Endothelial Cell-Specific Molecule-1 (ESM-1) as a New Potential Biomarker for Rheumatoid Arthritis Disease ActivityDoi: 10.2174/1874312901812010189
  • Downregulation of ENDOCAN in myeloid leukemia cells inhibits proliferation and promotes apoptosis by suppressing nuclear factor‑κB activityPubmed: 30816462
  • Endothelial biomarkers in the light of new sepsis definitionPubmed: 30920847
  • Risk stratification and prognostic evaluation of endothelial cell‑specific molecule1, von Willebrand factor, and a disintegrin‑like and metalloprotease with …
  • A novel marker relationship between carotid intima–media thickness and disease activity score-28 in patients with rheumatoid arthritis: human endothelial cell …Pubmed: 31655533
  • Role of Ascitic Endocan Levels in the Diagnosis of Spontaneous Bacterial Peritonitis in Decompensated CirrhosisPubmed: 32364003
  • Comparison of the maternal serum endocan levels in preterm premature rupture of membrane and normal pregnancy34109715
  • The relationship between serum endocan levels with the presence of contrast-induced nephropathy in patients undergoing coronary angiography

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