Eukaryotic Interleukin 31 (IL31) Canis familiaris; Canine (Dog) Eukaryotic protein

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Overview
Properties
  • Source Eukaryotic expression, Host 293F cell
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 16.2kDa, Accurate 22-35kDa(Analysis of differences refer to the manual)
  • Residues & TagsGln31~Gln159 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point6.3
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  • Eukaryotic Interleukin 31 (IL31) Packages (Simulation)
  • Eukaryotic Interleukin 31 (IL31) Packages (Simulation)
  • EPB179Ca62.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Increased serum levels of Interleukin-31 could modulate inflammatory processes in multiple sclerosisSiaic-Review:Source
  • Increased levels of interleukin 31 (IL-31) in osteoporosisPubMed: 2644965
  • Interleukin-31 expression and relation to disease severity in human asthmapmc:PMC4783779
  • Immediate-type allergic and protease-mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice.pubmed:28191683
  • The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction.pubmed:28067314
  • Immediate-type allergic and protease-media ted reactions are involved in scratching behavior induced by topical application of Dermatophagoides farinae extract in NC/Nga micedoi:10.1111
  • アトピー性皮膚炎の痒みの発症機序に関する研究
  • Determination the Role of Interleukin 31 (IL-31) Levels in Three Real Allergic Diseases (Asthma, Rhinitis, Urticaria)

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