Eukaryotic Permeability Glycoprotein (Pgp)

CD243; ABCB1; ABC20; CLCS; GP170; MDR1; PGY1; P-Glycoprotein; Multidrug resistance protein 1; ATP-Binding Cassette,Sub-Family B(MDR/TAP),Member 1; Colchicin Sensitivity

UOM
1. 10µg
2. 50µg
3. 200µg
4. 1mg
5. 5mg
FOB US$ 256.00 US$ 640.00 US$ 1,280.00 US$ 3,840.00 US$ 9,600.00
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Overview

Properties

Product No.EPB690Hu61
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
Applications Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Research use only
DownloadInstruction Manual
CategorySignal transduction CD & Adhesion molecule Tumor immunity Infection immunity

Source Eukaryotic expression, Host 293F cell
Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
Subcellular LocationMembrane
Molecular Mass 36.7kDa, Accurate 42&44kDa(Analysis of differences refer to the manual)
Residues & TagsMet68~Tyr116 with N-terminal His Tag and C-terminal Fc Region of Human IgG1
Buffer FormulationPBS, pH7.4, containing 5% Trehalose.
Traits Freeze-dried powder, Purity > 90%
Isoelectric Point3.6

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Packages (Simulation)
Packages (Simulation)

Figure. SDS-PAGE

ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Polyacrylamide Gel Electrophoresis (PAGE) Experiment Service

Increment services

Citations

P-glycoprotein promotes epithelial T helper 2–associated cytokine secretion in chronic sinusitis with nasal polypsOnlinelibrary: alr.21316
P‐glycoprotein regulates Staphylococcus aureus enterotoxin B–stimulated interleukin‐5 and thymic stromal lymphopoietin secretion in organotypic mucosal explantsPubMed: 26625351
Intact soluble P-glycoprotein is secreted by sinonasal epithelial cells.pubmed:27456593
Secreted P-glycoprotein is a noninvasive biomarker of chronic rhinosinusitispubmed:27577924
Design of colloidal drug carriers of celecoxib for use in treatment of breast cancer and leukemia
Chemotherapeutic drugs stimulate the release and recycling of extracellular vesicles to assist cancer cells in developing an urgent chemoresistancePubmed: 31830995