Eukaryotic Platelet Derived Growth Factor C (PDGFC) Homo sapiens (Human) Eukaryotic protein

PDGF-C; SCDGF; VEGF-E; Fallotein; Spinal cord-derived growth factor; Platelet-derived growth factor C, latent form; Platelet-derived growth factor C, receptor-binding form

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Overview
Properties
  • Source Eukaryotic expression, Host 293F cell
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Nucleus, Secreted, Cytoplasm
  • Molecular Mass 43.6kDa, Accurate 46kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal235-Gly345 with N-terminal His Tag and C-terminal Fc Region of Human IgG1
  • Buffer FormulationPBS, pH7.4, containing 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point7.8
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  • Eukaryotic Platelet Derived Growth Factor C (PDGFC) Packages (Simulation)
  • Eukaryotic Platelet Derived Growth Factor C (PDGFC) Packages (Simulation)
  • EPC920Hu61.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Platelet derived growth factor-CC secreted by M2 macrophages induces alpha-smooth muscle actin expression by dermal and gingival fibroblastsPubMed: 23182716
  • High glucose induces platelet‐derived growth factor‐C via carbohydrate response element‐binding protein in glomerular mesangial cellsPubmed:27033449
  • Changes in pulmonary endothelial cell properties during bleomycin-induced pulmonary fibrosisPubmed:29940932

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