Eukaryotic Vascular Endothelial Growth Factor Receptor 1 (VEGFR1)    
    
Flt1; Fms-Related Tyrosine Kinase 1; Vascular Permeability Factor Receptor; Fms-like tyrosine kinase 1; Tyrosine-protein kinase receptor FLT
Overview
Properties
- Product No.EPB818Hu63
 - Organism SpeciesHomo sapiens (Human) Same name, Different species.
 - 
                                Applications
                                Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Research use only - Downloadn/a
 - CategorySignal transductionTumor immunity
 
- Source Eukaryotic expression, Host 293F
 - Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
 - Subcellular LocationMembrane, Secreted
 - Molecular Mass 84.0kDa, Accurate 83kDa(Analysis of differences refer to the manual)
 - Residues & TagsSer27~Glu758 with N-terminal His Tag
 - Buffer FormulationPBS, pH7.4, containing 5% Trehalose.
 - Traits Freeze-dried powder, Purity > 90%
 - Isoelectric Point9.3
 
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            Sequence
Usage
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Storage
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Increment services
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                    BCA Protein Quantification Kit
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                    Protein Labeling Customized Service
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                    Molecular Mass Marker for Protein
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                    Monoclonal Antibody Customized Service
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                    Polyclonal Antibody Customized Service
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                    Protein Activity Test Experiment Service
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                    Immunoprecipitation (IP) Experiment Service
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                    Electrophoretic Mobility Shift Assay (EMSA) Experiment Service
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                    Buffer
                                 - 
                
                    Lentivirus Packaging Experiment Service
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                    Adenovirus Packaging Experiment Service
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                    Real Time PCR Experimental Service
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                    Spike RBD Protein (S-RBD)
                                 - 
                
                    Protein G
                                 - 
                
                    Protein A
                                 
Citations
- Growth Differentiation Factor 15 and Coronary Collateral FormationPubMed: 20014173
 - Mutant hypoxia inducible factor-1α improves angiogenesis and tissue perfusion in ischemic rabbit skeletal muscle PubMed: 20937289
 - Antiangiogenic Activities of Cinnamon, Black and Green Tea Extracts on Experimentally Induced Breast Cancer in RatsScialert: Source
 - Antioxidant and bone repair properties of quercetin-functionalized hydroxyapatite: an in vitro osteoblast-osteoclast-endothelial cell co-culture studyPubMed: 26689470
 - The multi-kinase inhibitor pazopanib targets hepatic stellate cell activation and apoptosis alleviating progression of liver fibrosisPubMed: 26269412
 - Antioxidant and bone repair properties of quercetin-functionalized hydroxyapatite: An in vitro osteoblast–osteoclast–endothelial cell co-culture studyPubmed:26689470
 - A Human 3D In Vitro Model to Assess the Relationship Between Osteoporosis and Disseminationto Bone of Breast Cancer Tumor Cells.pubmed:27925188
 - Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway.pubmed:29262624
 - Modulating circulating sFlt1 in an animal model of preeclampsia using PAMAM nanoparticles for siRNA delivery.pubmed:28962687
 - Synergistic effect of Si-hydroxyapatite coating and VEGF adsorption on Ti6Al4V-ELI scaffolds for bone regeneration in an osteoporotic bone environmentPubmed: 30445158
 - Association between Upper-airway Surgery and Ameliorative Risk Markers of endothelial function in obstructive Sleep ApneaPubmed: 31882827
 - Effect of isotretinoin (13-cis-retinoic acid) on levels of soluble VEGF receptors (sVEGFR1, sVEGFR2, sVEGFR3) in patients with acne vulgarisPubmed: 32043381
 - Cyclin G2 upregulation impairs migration, invasion, and network formation through RNF123/Dvl2/JNK signaling in the trophoblast cell line HTR8/SVneo, a possible …Pubmed: 33205477
 - sFlt-1/PlGF Ratio in Prediction of Short-Term Neonatal Outcome of Small for Gestational Age Neonates34438609
 - Reactive Oxygen Species are Essential for Placental Angiogenesis During Early GestationPubmed:35693704
 
