Eukaryotic Vitamin D Binding Protein (DBP) Homo sapiens (Human) Eukaryotic protein

GC; VDBG; VDBP; Group-Specific Component; Gc-globulin

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Overview
Properties
  • Source Eukaryotic expression, Host 293F cell
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 10.5kDa, Accurate 14kDa(Analysis of differences refer to the manual)
  • Residues & TagsGlu395~Leu474 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point4.6
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  • Eukaryotic Vitamin D Binding Protein (DBP) Packages (Simulation)
  • Eukaryotic Vitamin D Binding Protein (DBP) Packages (Simulation)
  • EPB810Hu61.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Isotope Coded Protein Labeling analysis of plasma specimens from acute severe dengue fever patientsPubMed: 23101585
  • Increased Circulating Levels of Vitamin D Binding Protein in MS PatientsPubmed:25590278
  • Vitamin D-binding protein and free vitamin D concentrations in acromegalyPubMed: 26547217
  • Comparative mass spectrometric and immunoassay‐based proteome analysis in serum of Duchenne muscular dystrophy patientsPubmed:26680509
  • 25-Hydroxivitamin D Serum Concentration, Not Free and Bioavailable Vitamin D, Is Associated with Disease Activity in Systemic Lupus Erythematosus Patients.pubmed:28085957
  • Comparative mass spectrometric and immunoassay-based proteome analysis in serum ofDuchenne muscular dystrophy patients.pubmed:26680509
  • 25-Hydroxivitamin D serum concentration, not free and bioavailable vitamin D, is associated with disease activity in systemic lupus erythematosus patients10.1371/journal.pone.0170323
  • Gene Expression of Sirtuin-1 and Endogenous Secretory Receptor for Advanced Glycation End Products in Healthy and Slightly Overweight Subjects after …Pubmed:30037068
  • Enhanced remedial effects for vitamin D3 and calcium co-supplementation against pre-existing lead nephrotoxicity in mice: The roles of renal calcium homeostatic …Pubmed: 30553018
  • Is Bioavailable Vitamin D Better Than Total Vitamin D to Evaluate Vitamin D Status in Obese Children?34013709
  • Leukocyte telomere length as a compensatory mechanism in vitamin D metabolismPubmed:35202418

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