Recombinant Fatty Acid Binding Protein 4 (FABP4) Homo sapiens (Human) Recombinant protein

A-FABP; AFABP; AP2; Fatty Acid Binding Protein 4, Adipocyte; Adipocyte Protein 2; Adipocyte-type fatty acid-binding protein

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationNucleus, Cytoplasm
  • Molecular Mass 15.8kDa, Accurate 16kDa(Analysis of differences refer to the manual)
  • Residues & TagsCys2~Ala132 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Point7.1
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  • Recombinant Fatty Acid Binding Protein 4 (FABP4) Packages (Simulation)
  • Recombinant Fatty Acid Binding Protein 4 (FABP4) Packages (Simulation)
  • Recombinant Fatty Acid Binding Protein 4 (FABP4) Figure . Gene Sequencing (extract)
  • RPB693Hu01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Enhanced A-FABP expression in visceral fat: potential contributor to the progression of NASHPubMed: 23091808
  • Siesta is associated with reduced systolic blood pressure level and decreased prevalence of hypertension in older adultsPubMed: 26134622
  • Overexpression of the A-FABP gene facilitates intermuscular fat deposition in transgenic micePubMed: 25867423
  • Cranberries (Oxycoccus quadripetalus) inhibit lipid metabolism and modulate leptin and adiponectin secretion in 3T3-L1 adipocytesPubMed: 25952883
  • Increased expression of fatty acid binding protein 4 in preeclamptic Placenta and its relevance to preeclampsiaPubmed:26992681
  • Valproate acid (VPA)-induced dysmetabolic function in clinical and animal studies.pubmed:28161274
  • Changes of Plasma FABP4, CRP, Leptin, and Chemerin Levels in relation to Different Dietary Patterns and Duodenal-Jejunal Omega Switch Surgery in Sprague …Pubmed:29849871
  • Lack of pronounced changes in the expression of fatty acid handling proteins in adipose tissue and plasma of morbidly obese humansPubmed:29335416
  • 25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4Pubmed: 31720079
  • Water Specific MRI T1 Mapping for Evaluating Liver Inflammation Activity Grades in Rats With Methionine‐Choline‐Deficient Diet‐Induced Nonalcoholic Fatty Liver …Pubmed:35212074
  • The Effect of Mineralocorticoid Receptor 3 Antagonists on Anti-Inflammatory and Anti-Fatty Acid Transport Profile in Patients with Heart FailurePubmed:35455943
  • FABP4 secreted by M1-polarized macrophages promotes synovitis and angiogenesis to exacerbate rheumatoid arthritisPubmed:35729106

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