Recombinant Fibulin 3 (FBLN3)
EFEMP1; DHRD; DRAD; FBNL; MLVT; MTLV; S1-5; EGF-Containing Fibulin-Like Extracellular Matrix Protein 1; Fibrillin-Like; Extracellular protein S1-5
Overview
Properties
- Product No.RPF422Hu01
- Organism SpeciesHomo sapiens (Human) Same name, Different species.
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Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Research use only - DownloadInstruction Manual
- CategoryMetabolic pathway
- Source Prokaryotic expression, Host E.coli
- Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
- Subcellular LocationSecreted, Extracellular matrix
- Molecular Mass 30.6kDa, Accurate 27kDa(Analysis of differences refer to the manual)
- Residues & TagsCys258~Phe493 with N-terminal His Tag
- Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- Traits Freeze-dried powder, Purity > 80%
- Isoelectric Point4.8
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Sequence

Usage
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
Storage
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Increment services
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Endotoxin Removal Kit
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BCA Protein Quantification Kit
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Protein Labeling Customized Service
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Molecular Mass Marker for Protein
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Recombinant Protein Customized Service
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Monoclonal Antibody Customized Service
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Polyclonal Antibody Customized Service
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Protein Activity Test Experiment Service
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Immunoprecipitation (IP) Experiment Service
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Buffer
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Endotoxin Removal Kit II
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Real Time PCR Experimental Service
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Spike RBD Protein (S-RBD)
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Protein G
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Protein A
Citations
- Fibulin-3 as a Blood and Effusion Biomarker for Pleural MesotheliomaPubMed: PMC3761217
- YKL-40 and mesothelin in the blood of patients with malignant mesothelioma, lung cancer and asbestosis.Pubmed: 24324091
- Role of fibulin-3 in lung cancer: In vivo and in vitro analysesSpandidos-publications: Source
- Discovery of new biomarkers for malignant mesotheliomaSpringer:Source
- DIAGNOSIS OF CELL PROLIFERATIVE DISEASESFreepatentsonline:Source
- Comparison of fibulin-3 and mesothelin as markers in malignant mesotheliomaPubmed:Pmc4174124
- Value of plasma and pleural effusion fibulin-3 levels in the diagnosis of malignant pleural mesothelioma effusionsPubmed:23050525
- Fibulin-3 as a biomarker of response to treatment in malignant mesotheliomaPubMed: 26401134
- Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosisPubMed: 26263483
- Plasma Biomarker Enrichment of Clinical Prognostic Indices in Malignant Pleural Mesothelioma.Pubmed:26903362
- Diagnostic and Prognostic Biomarkers in the Rational Assessment of Mesothelioma (DIAPHRAGM) study: protocol of a prospective, multicentre, observational study pubmed:27884852
- HMGB1 and its hyperacetylated isoform are sensitive and specific serum biomarkers to detect asbestos exposure and to identify mesothelioma patientspubmed:26733616
- Diagnostic and Prognostic Biomarkers in the Rational Assessment of Mesothelioma (DIAPHRAGM) study: protocol of a prospective, multicentre, observational …e013324.abstract
- Comparison of the Diagnostic Performance of Fibulin-3 and Mesothelin in Patients with Pleural Effusions from Malignant Mesothelioma.pubmed:28314308
- A Novel Panel of Serum Biomarkers for MPM Diagnosis.pubmed:28348450
- Association of fibulin-3 concentrations with the presence and severity of knee osteoarthritis: A cross-sectional studypubmed:29195846
- Plasma Fibulin-3 as a Potential Biomarker for Patients with Asbestos-Related Diseases in the Han Populationpubmed:29200597
- Placental protein 14 as a potential biomarker for diagnosis of preterm premature rupture of membranesPubmed:29749501
- The matrix protein Fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasionPubmed:30046386
- Fibulin-3 and other cartilage metabolism biomarkers in relationship to calprotectin (MRP8/14) and disease activity in rheumatoid arthritis patients treated with …68362.pdf
- Prediction of pneumoconiosis by serum and urinary biomarkers in workers exposed to asbestos-contaminated mineralsPubmed: 30946771