Recombinant Forkhead Box P3 (FOXP3)

FOX-P3; AIID; DIETER; IPEX; JM2; PIDX; XPID; SCURFIN; Forkhead Box Protein P3; Immune Dysregulation,Polyendocrinopathy,Enteropathy,X-Linked

UOM
1. 10µg
2. 50µg
3. 200µg
4. 1mg
5. 5mg
FOB US$ 172.00 US$ 430.00 US$ 860.00 US$ 2,580.00 US$ 6,450.00
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Overview

Properties

Product No.RPB877Hu01
Organism SpeciesHomo sapiens (Human) Same name, Different species.
- All
- Human
- Mouse
- Rat
- Cavia
- Rabbit
- Simian
- Canine
- Porcine
- Bovine
- Caprine
- Multi-species
- Pan-species
- Others
Applications Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Research use only
DownloadInstruction Manual
CategorySignal transduction Apoptosis Tumor immunity Infection immunity Immune molecule

Source Prokaryotic expression, Host E.coli
Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
Subcellular LocationNucleus
Molecular Mass 29.1kDa, Accurate 29kDa(Analysis of differences refer to the manual)
Residues & TagsTyr191~Glu412 with N-terminal His Tag
Buffer Formulation100mMNaHCO3, 500mMNaCl, pH8.3, containing 0.01% SKL, 5% Trehalose.
Traits Freeze-dried powder, Purity > 97%
Isoelectric Point7.8

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Packages (Simulation)
Packages (Simulation)

Figure . Gene Sequencing (extract)

Figure. SDS-PAGE

ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in ddH₂O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Giveaways

Polyacrylamide Gel Electrophoresis (PAGE) Experiment Service

Increment services

Citations

Dichloroacetate at therapeutic concentration alters glucose metabolism and induces regulatory T-cell differentiation in alloreactive human lymphocytesPubmed: 23612652
Genetic Polymorphisms of Foxp3 in Patients with Rheumatoid ArthritisPubmed:25448791#
Increasing Foxp3, IgG4 and improvement quality of life after immunotherapy treatment in allergic rhinitis patientsarticle:30785
The Role of T-Regulatory Expression in Autoimmune Thyroid Disease and its Association with Thyroid _x005f_x0004_Antibodythe-role-of-tregulatory-expression-in-autoimmune-t
gene polymorphisms and its protein level in patients with rheumatoid arthritis: a case–control studyPubmed:29411043
Therapeutic potential of tranilast for the treatment of chronic graft-versus-host disease in micePubmed: 30307955
Toll-Like Receptor 4–Myeloid Differentiation Primary Response Gene 88 Pathway Is Involved in the Shikonin Treatment of CIA by Regulating Treg/Th17 ExpressionDoi: 10.1155/2018/2428546
Alteration of oxidative-stress and related marker levels in mouse colonic tissues and fecal microbiota structures with chronic ethanol administration ¡33577585