Recombinant Hypoxia Inducible Factor 2 Alpha (HIF2a) Mus musculus (Mouse) Recombinant protein

EPAS1; HLF; MOP2; PASD2; BHLHE73; Endothelial PAS Domain 1; HIF-1 Alpha-Like Factor; Basic-helix-loop-helix-PAS protein MOP2; Class E basic helix-loop-helix protein 73

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationNucleus
  • Molecular Mass 37.2kDa, Accurate 37kDa(Analysis of differences refer to the manual)
  • Residues & TagsAsp21~Cys336 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Point6.4
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  • Recombinant Hypoxia Inducible Factor 2 Alpha (HIF2a) Packages (Simulation)
  • Recombinant Hypoxia Inducible Factor 2 Alpha (HIF2a) Packages (Simulation)
  • Recombinant Hypoxia Inducible Factor 2 Alpha (HIF2a) Figure. Gene Sequencing (Extract)
  • RPD466Mu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Combination viroimmunotherapy with checkpoint inhibition to treat glioma, based on location-specific tumor profilingPubMed: 26409567
  • Correlating oxidative stress-related factors with bone metabolic markers in older adult male patients exhibiting degenerative osteoporosis in the high-altitude hypoxic area of China: study protocol for a non-randomized controlled trialissn:2542-3975
  • Telomere elongation protects heart and lung tissue cells from fatal damage in rats exposed to severe hypoxiaPubmed:29454386
  • Oxidative damage and iron dyshomeostasis in thalassemic patients
  • The Association Between Hypoxia Improvement and Electroconvulsive Therapy for Major Depressive Disorder34588778

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