Recombinant Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Homo sapiens (Human) Recombinant protein

FSTL2; IGFBP-7v; MAC25; PSF; TAF; IGFBP-rP1; MAC25 protein; Prostacyclin-stimulating factor; PGI2-stimulating factor; Tumor-derived adhesion factor

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 22.7kDa, Accurate 25kDa(Analysis of differences refer to the manual)
  • Residues & TagsSer24~Leu50+Gly130~Leu282 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point6.1
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  • Recombinant Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Packages (Simulation)
  • Recombinant Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Packages (Simulation)
  • Recombinant Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Figure . Gene Sequencing (extract)
  • RPB673Hu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial CellsPubmed:26974954
  • Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells.pubmed:26974954
  • Urine-Based Biomarkers for Alzheimer's Disease Identified Through Coupling Computational and Experimental MethodsPubmed:30040720
  • IGFBP7 Drives Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition in Lung CancerPubmed: 30609749
  • Insulin-like growth factor-binding protein 7 (IGFBP 7) as a new biomarker in coronary heart diseasePubmed: 30769262
  • Altered insulin-like growth factor-2 signaling is associated with psychopathology and cognitive deficits in patients with schizophreniaPubmed: 32191705
  • Discovery of novel biomarkers for atherosclerotic aortic aneurysm through proteomics-based assessment of disease progressionPubmed: 32286426
  • SNORD116 and growth hormone therapy impact IGFBP7 in Prader¨CWilli syndrome34040195
  • Biomarkers of persistent renal vulnerability after acute kidney injury recovery34707157
  • IGFBP7 Concentration May Reflect Subclinical Myocardial Damage and Kidney Function in Patients with Stable Ischemic Heart DiseasePubmed:35204773
  • Insulin-Like Growth Factor-Binding Protein 7 (IGFBP-7)—New Diagnostic and Prognostic Marker in Symptomatic Peripheral Arterial Disease?—Pilot StudyPubmed:35625639

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