Recombinant Insulin Receptor (INSR) Homo sapiens (Human) Recombinant protein

CD220; ISR; HHF5; IR

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 37.7kDa, Accurate 40kDa(Analysis of differences refer to the manual)
  • Residues & TagsPro622~Thr945 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point5.6
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  • Recombinant Insulin Receptor (INSR) Packages (Simulation)
  • Recombinant Insulin Receptor (INSR) Packages (Simulation)
  • Recombinant Insulin Receptor (INSR) Figure . Gene Sequencing (extract)
  • RPA895Hu03.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Molecular and Biochemical Effect of Neem Extract On Experimental Diabetes Org:Source
  • Age-Dependent Onset of Insulin Resistance in Insulin-Resistant MicePubMed: 26632184
  • A newly developed silymarin nanoformulation as a potential antidiabetic agent in experimental diabetespubmed:27623396
  • Subcutaneous liraglutide ameliorates methylglyoxal-induced Alzheimer-like tau pathology and cognitive impairment by modulating tau hyperphosphorylation and glycogen synthase kinase-3β.pubmed:28337257
  • Vitamin D3 intake as regulator of insulin degrading enzyme and insulin receptor phosphorylationin diabetic rats.pubmed:27930980
  • Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment.pubmed:28063625
  • (台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探
  • Mechanism underlying starvation-dependent modulation of olfactory behavior in Drosophila larvaPubmed: 32080342
  • Prenatal Stress Induced Spatial Memory Deficit in a Sex-Specific Manner in Mice: Possible Involvement of Hippocampal Insulin Resistance
  • Internal State Affects Local Neuron Function in an Early Sensory Processing Center to Shape Olfactory Behavior in Drosophila Larvae

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