Recombinant Interleukin 18 Binding Protein (IL18BP) Rattus norvegicus (Rat) Recombinant protein

IL18BPa; MC51L-53L-54L Homolog Gene Product; Tadekinig-alfa

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 19.4kDa, Accurate 21kDa(Analysis of differences refer to the manual)
  • Residues & TagsThr29~Pro193 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point6.8
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  • Recombinant Interleukin 18 Binding Protein (IL18BP) Packages (Simulation)
  • Recombinant Interleukin 18 Binding Protein (IL18BP) Packages (Simulation)
  • Recombinant Interleukin 18 Binding Protein (IL18BP) Figure . Gene Sequencing (extract)
  • RPH821Ra01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in micePubmed:25182570
  • Role of IL‐18 in atopic asthma is determined by balance of IL‐18/IL‐18BP/IL‐18RPubmed:28922563
  • Altered expression of IL‐18 binding protein and IL‐18 receptor in basophils and mast cells of asthma patientsPubmed:29505668
  • IL-18 binding protein (IL-18BP) as a novel radiation countermeasure after radiation exposure in micePubmed: 33129789

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