Recombinant Interleukin 24 (IL24) Rattus norvegicus (Rat) Recombinant protein

C49A; FISP; IL10B; MDA7; Mob-5; ST16; Mda-7; Melanoma Differentiation Association Protein 7; Suppression Of Tumorigenicity 16

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted
  • Molecular Mass 48.0kDa, Accurate 48kDa(Analysis of differences refer to the manual)
  • Residues & TagsGln29~Leu183 with N-terminal His and GST Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point8.4
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  • Recombinant Interleukin 24 (IL24) Packages (Simulation)
  • Recombinant Interleukin 24 (IL24) Packages (Simulation)
  • Recombinant Interleukin 24 (IL24) Gene sequencing
  • RPC064Ra01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Oncolytic adenovirus armed with IL-24 Inhibits the growth of breast cancer in vitro and in vivoPubMed: PMC3511263
  • Improving the mda-7/IL-24 refolding and purification process using optimized culture conditions based on the structure characteristics of inclusion bodiesSpringer:Source
  • Inhibition of ALDH2 protects PC12 cells against formaldehyde-induced cytotoxicity: involving the protection of hydrogen sulphide.pubmed:28251688
  • IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer33456560
  • IL-24 inhibits the malignancy of human glioblastoma cells via destabilization of Zeb133894112
  • Interleukin-24 regulates mucosal remodeling in inflammatory bowel diseases34078403
  • Effect of Serum Spermidine on the Prognosis in Patients with Acute Myocardial Infarction: A Cohort StudyPubmed:35406007

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