KLH Conjugated Procollagen I N-Terminal Propeptide (PINP) Homo sapiens (Human) Conjugated small molecules

P1NP; N-Propeptide Of Type I Procollagen; Procollagen I Amino Terminal Propeptide

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Overview
Properties
  • SourceProtein Conjugation
  • Original Molecular Massn/a
  • Buffer FormulationPBS, pH7.4.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Pointn/a
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  • KLH Conjugated Procollagen I N-Terminal Propeptide (PINP) Packages (Simulation)
  • KLH Conjugated Procollagen I N-Terminal Propeptide (PINP) Packages (Simulation)
  • KLH Conjugated Procollagen I N-Terminal Propeptide (PINP)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Formula

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Is there benefit in optimising heart failure treatment in over-80 year-old patients? (HF-80 study): study protocol for a randomized controlled trial.Trials: 1745-6215
  • Measurement of aminoterminal propeptide of type I procollagen (PINP) in serumScienceDirect: S0009912012001543
  • Low molecular weight iron dextran increases fibroblast growth factor-23 concentration, together with parathyroid hormone decrease in hemodialyzed patientsPubMed: 22458393
  • IL4 and IL-17A provide a Th2/Th17-polarized inflammatory milieu in favor of TGF-β1 to induce bronchial epithelial-mesenchymal transition (EMT)PubMed: PMC3726963
  • PINP as a biological response marker during teriparatide treatment for osteoporosisPubmed: 24599274
  • Zoledronic acid has differential anti-tumour activity in the pre-and post-menopausal bone microenvironment in vivoAacrjournals: Source
  • Oxytocin Reverses Ovariectomy-Induced Osteopenia and Body Fat GainEndocrine: Source
  • Oxytocin reverse ovariectomy-induced Osteoper and body fat gainPubmed:24506069
  • The effect of topiramate and lamotrigine on rat bone mass, structure and metabolism.Pubmed:24629477
  • Neurofibromin inactivation impairs osteocyte development in Nf1Prx1 and Nf1Col1 mouse modelsPubmed:24947449
  • Phosphatidylethanolamine biomimetic coating increases mesenchymal stem cell osteoblastogenesisPubmed:24980874
  • Effects of de-escalated bisphosphonate therapy on bone turnover biomarkers in breast cancer patients with bone metastasesPubmed:25332877
  • Effect of Mirtazapine on Rat Bone Tissue after OrchidectomyPubMed: 25871861
  • Oxytocin reverses osteoporosis in a sex-dependent mannerPubMed: 26042090
  • Changes in Bone Metabolism Months after Laparoscopic Morbidly Obese Pre-menopausal WomenMms: Content
  • Prognostic value of collagen turnover biomarkers in cardiac resynchronization therapy: A subanalysis of the TRUST CRT randomized trial populationPubmed:26776557
  • Procollagen markers in microdialysate can predict patient outcome after Achilles tendon rupturecontent:2
  • Bilaterale Kommunikation zwischen Osteoblasten und Osteoklastenvolltexte:2016
  • Fibrosis of extracellular matrix is related to the duration of the disease but is unrelated to the dynamics of collagen metabolism in dilated cardiomyopathypubmed:27516211
  • Bone turnover response is linked to both acute and established metabolic changes in ultra-marathon runnerspubmed:27422791
  • Left ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRRpubmed:28004175
  • The effect of calcium and vitamin D supplementation on bone health of male Jockeys.pubmed:27568072
  • Combined aerobic and resistance training improves bone health of female cancer survivorsS2352187216300389
  • Renal Denervation Attenuates Multi-Organ Fibrosis and Improves Vascular Remodeling in Rats with Transverse Aortic Constriction Induced Cardiomyopathypubmed:27889753
  • The effect of lamotrigine and phenytoin on bone turnover and bone strength: A prospective study in Wistar ratspubmed:27838501
  • Sprint Interval Training Induces A Sexual Dimorphism but does not Improve Peak Bone Mass in Young and Healthy Mice.pubmed:28303909
  • Low periostin levels in adult patients with Langerhans cell histiocytosis are independently associated with the disease activity.pubmed:28521873
  • Erratum to: Effects on bone metabolism markers and arterial stiffness by switching to rivaroxaban from warfarin in patients with atrial fibrillationpubmed:28314975
  • A Study Protocol: Spinal Morphology, Physical Performance, Quality of Life and Biochemical Markers in Adults at Risk of Osteoporotic Fractures 59f7c85aaca272607e2d8d7a
  • Achilles tendon rupture healing is enhanced by intermittent pneumatic compression upregulating collagen type I synthesispubmed:28668970
  • Method for the treatment of cardiovascular fibrosispatents:US9594083
  • Periostin and sclerostin levels in juvenile Paget's diseasepubmed:29263750
  • Congenital Hypothyroidism and Bone Remodeling Cyclepubmed:27840329
  • Relationship of biomarkers of extracellular matrix with myocardial function in Type 2 diabetes mellituspubmed:28685602
  • Left ventricular reverse remodeling is not related to biopsy‑detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR10.1007/s00380-016-0930-y
  • Optimization of the Time Window of Interest in Ovariectomized Imprinting Control Region Mice for Antiosteoporosis Researchpubmed:29119115
  • 12-month patterns of serum markers of collagen synthesis, transforming growth factor and connective tissue growth factor are similar in new-onset and chronic dilated cardiomyopathy in patients both with and without cardiac fibrosis.pubmed:28460256
  • Prognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events.pubmed:29120858
  • The key role of proinflammatory cytokines, matrix proteins, RANKL/OPG and Wnt/β-catenin in bone healing of hip arthroplasty patientspubmed:29129760
  • TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42Pubmed:29358671
  • Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women—A Randomized Controlled StudyPubmed:29337906
  • Two-year cortical and trabecular bone loss in CKD-5D: biochemical and clinical predictorsPubmed:28993865
  • Cholecalciferol Supplementation Promotes Bone Turnover in Chinese Adults with Vitamin D DeficiencyPubmed:29897564
  • The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolismPubmed:29428468
  • Geometric and mechanical bone response to a multidisciplinary weight loss intervention in adolescents with obesity: The ADIBOX studyPubmed:30076009
  • Circulating matrix metalloproteinases and procollagen propeptides in inguinal herniaPubmed:29484522
  • Effects of Amlodipine on Bone Metabolism in Orchidectomised Spontaneously Hypertensive RatsPubmed:29898457
  • Coupling of bone resorption and formation by RANKL reverse signallingPubmed: 30185903
  • Biomechanical and histological analyses of the fracture healing process after direct or prolonged reductionPubmed: 30180907
  • Membrane-Based Microwave-Mediated Electrochemical Immunoassay for the In Vitro, Highly Sensitive Detection of Osteoporosis-Related BiomarkersPubmed: 30181433
  • Structured diet and exercise guidance in pregnancy to improve health in women and their offspring: study protocol for the Be Healthy in Pregnancy (BHIP) …Pubmed: 30567604
  • Effect of induction therapy with lenalidomide, doxorubicin, and dexamethasone on bone remodeling and angiogenesis in newly diagnosed multiple myelomaPubmed: 30650184
  • Rapamycin improves bone mass in high-turnover osteoporosis with iron accumulation through positive effects on osteogenesis and angiogenesisPubmed: 30610968
  • Quantification of N-Terminal Procollagen I Propeptide in Patients With Occlusal Trauma Induced by Prosthetic Factors
  • Effect of antibiotic infused calcium sulfate/hydroxyapatite (CAS/HA) insets on implant-associated osteitis in a femur fracture model in micePubmed: 30870491
  • Low fibrosis biomarker levels predict cardiac resynchronization therapy responsePubmed: 30988339
  • Changes in Calciotropic Hormones and Bone Markers During Pregnancy in Response to a Nutrition+ Exercise Intervention in the Be Healthy in Pregnancy RCT (P11 …Pubmed: 31224444
  • Low concentration flufenamic acid enhances osteogenic differentiation of mesenchymal stem cells and suppresses bone loss by inhibition of the NF-κB …Pubmed: 31324207
  • The long noncoding RNA Crnde regulates osteoblast proliferation through the Wnt/β-catenin signaling pathway in micePubmed: 31622775
  • Expression of prolactin receptors in the duodenum, kidneys and skeletal system during physiological and sulpiride-induced hyperprolactinaemiaPubmed: 30143940
  • Mice lacking plastin-3 display a specific defect of cortical bone acquisitionPubmed: 31678489
  • Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic PatientsPubmed: 31717649
  • BMP9 reduces bone loss in ovariectomized mice by dual regulation of bone remodelingPubmed: 31914211
  • Outcome in German and South African peripartum cardiomyopathy cohorts associates with medical therapy and fibrosis markersPubmed: 32064780
  • Hypoalbuminemia differently affects the serum bone turnover markers in hemodialysis patientsPubmed: 31839746
  • Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone FormationPubmed: 33180356
  • Extracellular matrix collagen biomarkers levels in patients with chronic thromboembolic pulmonary hypertensionPubmed: 33175289
  • Development of a novel polysaccharide-based iron oxide nanoparticle to prevent iron accumulation-related osteoporosis by scavenging reactive oxygen …Pubmed: 33049237
  • Mice carrying a ubiquitous R235W mutation of Wnt1 display a bone‐specific phenotypePubmed: 32369212
  • FGF23 and primary hyperparathyroidism: is there a link?Pubmed: 32598019
  • Qu Feng Zhi Tong capsule increases mechanical properties of cortical bone in ovariectomized rats
  • 4-Hexylresorcinol Inhibits Osteoclastogenesis by Suppressing NF‐κB Signaling Pathway and Reverses Bone Loss in Ovariectomized Mice
  • 淫羊藿水提物及提取药渣的抗骨质疏松药效比较研究
  • Postmenapozal Tip-2 diyabetes mellitus' lu hastalarda osteoporoza bağlı kırık riskinin ve kemik Turnoveri'nin değerlendirilmesi
  • Bone Turnover Markers in Osteogenesis Imperfecta and Effect of Bisphosphonate Treatment: First Egyptian Study
  • A biomimetically hierarchical polyetherketoneketone scaffold for osteoporotic bone repair33310848
  • Proinflammatory and bone protective role of calcitonin gene-related peptide alpha in collagen antibody-induced arthritis33221885
  • Low Energy Availability with and without a High-Protein Diet Suppresses Bone Formation and Increases Bone Resorption in Men: A Randomized Controlled Pilot ¡­33671093
  • Lgr4 promotes aerobic glycolysis and differentiation in osteoblasts via the canonical Wnt/¦Â©\catenin pathway33950533
  • Randomized, double-blind, placebo-controlled trial to examine the safety, pharmacokinetics and effects of Epimedium prenylflavonoids, on bone specific alkaline …34352588
  • The Effect of Daily Methylsulfonylmethane (MSM) Consumption on High-Density Lipoprotein Cholesterol in Healthy Overweight and Obese Adults: A Randomized …34684621
  • Osteoblast-specific inactivation of p53 results in locally increased bone formation34793446
  • The WNT1G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XV34759273
  • The Effect of Caloric Restriction with and without n-3 PUFA Supplementation on Bone Turnover Markers in Blood of Subjects with Abdominal Obesity: A Randomized …34578973
  • Night shift work and osteoporosis-bone turnover markers among female blue-collar workers in PolandPubmed:35139709
  • Spine Metastases in Immunocompromised Mice after Intracardiac Injection of MDA-MB-231-SCP2 Breast Cancer CellsPubmed:35158823
  • BMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axisPubmed:35523787
  • Foxf2 represses bone formation via Wnt2b/β-catenin signalingPubmed:35668101
  • Osteoporotic bone recovery by a bamboo-structured bioceramic with controlled release of hydroxyapatite nanoparticlesPubmed:35386445
  • Puerarin specifically disrupts osteoclast activation via blocking integrin-β3 Pyk2/Src/Cbl signaling pathwayPubmed:35228997
  • Construction of a magnesium hydroxide/graphene oxide/hydroxyapatite composite coating on Mg–Ca–Zn–Ag alloy to inhibit bacterial infection and promote …Pubmed:35585377
  • Exercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35 …

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