Recombinant Karyopherin Alpha 2 (KPNa2) Homo sapiens (Human) Recombinant protein

IPOA1; QIP2; RCH1; SRP1alpha; RAG Cohort 1; Importin Alpha 1; RAG cohort protein 1; SRP1-alpha

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationNucleus, Cytoplasm
  • Molecular Mass 31.0kDa, Accurate 27kDa(Analysis of differences refer to the manual)
  • Residues & TagsAla157~Gln412 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Point5.0
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  • Recombinant Karyopherin Alpha 2 (KPNa2) Packages (Simulation)
  • Recombinant Karyopherin Alpha 2 (KPNa2) Packages (Simulation)
  • Recombinant Karyopherin Alpha 2 (KPNa2) Figure. Gene Sequencing (Extract)
  • RPE748Hu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • KPNA2 is a promising biomarker candidate for esophageal squamous cell carcinoma and correlates with cell proliferationPubmed:25109899
  • KPNA2 is a potential diagnostic serum biomarker for epithelial ovarian cancer and correlates with poor prognosispubmed:28651492
  • Association of overexpressed karyopherin alpha 2 with poor survival and its contribution to interleukin‐1β‐induced matrix metalloproteinase expression in oral cancerPubmed:29542209
  • Nuclear transport proteins are secreted by cancer cells and identified as potential novel cancer biomarkers34591985

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