Recombinant Lectin Like Oxidized Low Density Lipoprotein Receptor 1 (LOX1) Bos taurus; Bovine (Cattle) Recombinant protein

OLR1; CLEC8A; SCARE1; Oxidized low-density lipoprotein receptor 1; C-type lectin domain family 8 member A; Lectin-like oxidized LDL receptor 1; Lectin-type oxidized LDL receptor 1

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane, Secreted
  • Molecular Mass 28.5kDa, Accurate 29kDa(Analysis of differences refer to the manual)
  • Residues & TagsSer57~Gln270 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 97%
  • Isoelectric Point29kDa
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  • Recombinant Lectin Like Oxidized Low Density Lipoprotein Receptor 1 (LOX1) Packages (Simulation)
  • Recombinant Lectin Like Oxidized Low Density Lipoprotein Receptor 1 (LOX1) Packages (Simulation)
  • RPB859Bo01.jpg SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels Are Associated With Angiographic Coronary Lesion Complexity in Patients With Coronary Artery DiseasPubMed: 21400544
  • Postprocedural serum sLOX-1 levels are associated with coronary in-stent restenosis in patients with stable coronary artery diseaseLWW: 06000
  • Soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in synovial fluid are correlated with disease severity of knee osteoarthritisScienceDirect: S0009912011004905
  • Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive AgePubMed: 22619487
  • Lectin-like oxidized low density lipoprotein receptor 1(LOX-1) levels and endothelial dysfunction in patients with primary essential hyperhidrosis/Primer esansiyel hiperhidroz hastalarinda lektin benzeri okside düsük dansiteli lipoprotein reseptor 1(LOX-1) düzeyleri ve endotel disfonksiyonuReadperiodicals: Source
  • Soluble Lectin-Like Oxidized LDL Receptor 1 as a Possible Mediator of Endothelial Dysfunction in Patients With Metabolic SyndromePubmed:24798146
  • Endothelial damage in white coat hypertension: role of lectin-like oxidized low-density lipoprotein-1Pubmed:25007999
  • Inhibition of Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Protects against Plasma/Hypoxia-Mediated Trophoblast Dysfunction Associated with PreeclampsiaPubmed:25633310
  • Increased serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with biopsy-proven nonalcoholic fatty liver diseasePubMed: 26185381
  • Serum sLOX-1 Levels Are Correlated with the Presence and Severity of Obstructive Sleep ApneaPubMed: 25825846
  • 27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells.pubmed:28167099
  • Increased Levels of Lectin‐Like Oxidized Low‐Density Lipoprotein Receptor‐1 in Ischemic Stroke and Transient Ischemic AttackPubmed:29330254
  • Higher serum lectin-like oxidized low-density lipoprotein receptor-1 in patients with stable coronary artery disease is associated with major adverse …
  • Baseline Serum sLOX-1 Concentrations Are Associated with 2-Year Major Adverse Cardiovascular and Cerebrovascular Events in Patients after Percutaneous …Pubmed: 31772687
  • Polycystic ovary syndrome and endothelial dysfunction: A potential role for soluble lectin-like oxidized low density lipoprotein receptor-1Pubmed: 32409108
  • The oxidized‐LDL/LOX‐1 axis in tumor endothelial cells enhances metastasis by recruiting neutrophils and cancer cellsPubmed:35608341

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