Recombinant Lysyl Oxidase (LOX) Mus musculus (Mouse) Recombinant protein

Protein-Lysine 6-Oxidase

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationSecreted, Extracellular matrix
  • Molecular Mass 55.4kDa, Accurate 54kDa(Analysis of differences refer to the manual)
  • Residues & TagsPro207~Tyr411 with N-terminal His and GST Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point6.1
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  • Recombinant Lysyl Oxidase (LOX) Packages (Simulation)
  • Recombinant Lysyl Oxidase (LOX) Packages (Simulation)
  • Recombinant Lysyl Oxidase (LOX) Figure . Gene Sequencing (extract)
  • RPC580Mu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • The expression of lysyl-oxidase gene family members in myeloproliferative neoplasms.PubMed: 23494965
  • High Glucose Induced Differential Expression of Lysyl Oxidase and Its Isoform in ARPE-19 CellsPubmed: 22966818
  • Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed: 24246612
  • Copia autorizada por CDRIngentaconnect: Source
  • Lysyl oxidase is a potential biomarker of fibrosis in systemic sclerosisPubmed: 24574233
  • Evaluation of serum lysyl oxidase as a blood test for colorectal cancerPubmed:Pmc4237001
  • Ionizing radiation induces tumor cell lysyl oxidase secretionPubmed:Pmc4223762
  • Lysyl Oxidase Genetic Variants Affect Gene Expression in Cervical CancerPubmed:24945327
  • Increased Serum Levels of the IL-33 Neutralizing sST2 in Limited Cutaneous Systemic SclerosisPubMed: 26095613
  • Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in PseudoexfoliationPubmed:27116380
  • LOX Fails to Substitute for RANKL in Osteoclastogenesis.pubmed:27606829
  • Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases.pubmed:28445728
  • Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen‑induced arthritispubmed:28901438
  • A Global Assessment of Circulating Prolysyl Oxidase in Nonischemic Patients With Garden-variety Heart Failure With Preserved Ejection FractionPubmed:29807761
  • Lysyl oxidase inhibition via β-aminoproprionitrile hampers human umbilical vein endothelial cell angiogenesis and migration in vitroPubmed:29393489
  • Lysyl Oxidase is a key player in BRAF/MAPK pathway-driven thyroid cancer aggressivenessPubmed: 30398411
  • Lysyl Oxidase Directly Contributes to Extracellular Matrix Production and Fibrosis in Systemic Sclerosis.Pubmed: 33026236
  • Collagen Cross©\Linking Is Associated With Cardiac Remodeling in Hypertrophic Obstructive Cardiomyopathy33356379

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