Recombinant Cluster Of Differentiation 146 (CD146) Homo sapiens (Human) Recombinant protein

MCAM; MUC18; Melanoma Cell Adhesion Molecule; Cell surface glycoprotein P1H12; Melanoma-associated antigen A32; S-endo 1 endothelial-associated antigen

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Molecular Mass 27.9kDa, Accurate 33kDa(Analysis of differences refer to the manual)
  • Residues & TagsAsp324~Val565 with N-terminal His Tag
  • Buffer FormulationPBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
  • Traits Freeze-dried powder, Purity > 90%
  • Isoelectric Point5.1
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  • Recombinant Cluster Of Differentiation 146 (CD146) Packages (Simulation)
  • Recombinant Cluster Of Differentiation 146 (CD146) Packages (Simulation)
  • RPB670Hu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Evaluation of various endothelial biomarkers in ankylosing spondylitisPubMed: 21556780
  • The Effect of Regular Colchicine Treatment on Biomarkers Related with Vascular Injury in Newly Diagnosed Patients with Familial Mediterranean FeverSpringerLink: m7128503g576w808
  • Selective targeting of liver cancer with the endothelial marker CD146Pubmed:25238265
  • Melanoma cell adhesion molecule as an emerging biomarker with prognostic significance in systolic heart failurepubmed:27355366

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